学位
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博士（理学） （ 北海道大学 ）
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修士(工学) （ 東京農工大学 ）
所属
学部 総合数理学部 専任准教授
職名
専任准教授
外部リンク
経歴
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明治大学 総合数理学部 准教授
所属学協会
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日本蛋白質科学会
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日本生物物理学会
論文
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Partially induced transition from horizontal to vertical orientation of helical peptides at the air-water interface and the structure of their monolayers transferred on the solid substrates. 査読
Kato N, Sasaki T, Mukai Y
Biochimica et biophysica acta 1848 ( 4 ) 967 - 975 2015年4月
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Relationship between the reconstituted vesicle size and the transmembrane protein-to-lipid ratio 査読
Noritaka Kato, Shunsuke Kimura, Takanori Sasaki
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 460 510 - 515 2014年10月
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pH-Dependent Interactions between Membrane and Histidine-containing Peptides
Noritaka Kato, Tomohiro Kawamata, Takanori Sasaki, Yuri Mukai
CHEMISTRY LETTERS 41 ( 10 ) 1193 - 1195 2012年10月
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Vertically oriented α-helical peptides in Langmuir-Blodgett films
佐々木 貴規, K. Togashi, T. Iizuka, S. Yanagiya, N. Kato, T. Sasaki, Y. Mukai
e-Journal of Surface Science and Nanotechnology 10 379 - 387 2012年7月
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A Computational Identification Method for GPI-Anchored Proteins by Artificial Neural Network
Yuri Mukai, Hirotaka Tanaka, Masao Yoshizawa, Osamu Oura, Takanori Sasaki, Masami Ikeda
CURRENT BIOINFORMATICS 7 ( 2 ) 125 - 131 2012年6月
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Homotrimer Formation and Dissociation of pharaonis Halorhodopsin in Detergent System
Takashi Tsukamoto, Takanori Sasaki, Kazuhiro J. Fujimoto, Takashi Kikukawa, Masakatsu Kamiya, Tomoyasu Aizawa, Keiichi Kawano, Naoki Kamo, Makoto Demura
BIOPHYSICAL JOURNAL 102 ( 12 ) 2906 - 2915 2012年6月
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Characteristics of Halorhodopsin-Bacterioruberin Complex from Natronomonas pharaonis Membrane in the Solubilized System
Takanori Sasaki, Nur Wahida Abdul Razak, Noritaka Kato, Yuri Mukai
BIOCHEMISTRY 51 ( 13 ) 2785 - 2794 2012年4月
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Fabrication of Langmuir-Blodgett Films Using Amphiphilic Peptides
Ken Togashi, Takumi Iizuka, Noritaka Kato, Takanori Sasaki, Yuri Mukai
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 12 ( 1 ) 568 - 572 2012年1月
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Sensitive detection of protein-lipid interaction change on bacteriorhodopsin using dodecyl β-D-maltoside
佐々木 貴規, T.Sasaki, M. Demura, N. Kato, Y. Mukai
Biochemistry 50 ( 12 ) 2283 - 2290 2011年3月
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Discrimination of Golgi Type II Membrane Proteins Based on Their Hydropathy Profiles and the Amino Acid Propensities of Their Transmembrane Regions
Yuri Mukai, Masao Yoshizawa, Takanori Sasaki, Masami Ikeda, Kentaro Tomii, Takatsugu Hirokawa, Makiko Suwa
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 75 ( 1 ) 82 - 88 2011年1月
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Effect of Chloride Binding on the Thermal Trimer-Monomer Conversion of Halorhodopsin in the Solubilized System
Takanori Sasaki, Tomoyasu Aizawa, Masakatsu Kamiya, Takashi Kikukawa, Keiichi Kawano, Naoki Kamo, Makoto Demura
BIOCHEMISTRY 48 ( 51 ) 12089 - 12095 2009年12月
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Halorhodopsin from Natronomonas pharaonis forms a trimer even in the presence of a detergent, Dodecyl-β-D-maltoside
佐々木 貴規, T. Sasaki, M. Kubo, T. Kikukawa, M. Kamiya, T. Aizawa, K. Kawano, N. Kamo, M. Demura
Photochemistry and Photobiology 85 ( 1 ) 130 - 136 2009年1月
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Electrophoresis of Dyes and Proteins in Poly(Acrylamide) Gel Containing Immobilized Bilayer Membranes
Hiroki Ishihara, Goh Matsuo, Takanori Sasaki, Yuko Saito, Makoto Demura, Kaoru Tsujii
GELS: STRUCTURES, PROPERTIES, AND FUNCTIONS 136 143 - + 2009年
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Hydrogen-bonding alterations of the protonated Schiff base and water molecule in the chloride pump of Natronobacterium pharaonis
M Shibata, N Muneda, T Sasaki, K Shimono, N Kamo, M Demura, H Kandori
BIOCHEMISTRY 44 ( 37 ) 12279 - 12286 2005年9月
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Photobleaching of bacteriorhodopsin solubilized with Triton X-100
T Sasaki, M Sonoyama, M Demura, S Mitaku
PHOTOCHEMISTRY AND PHOTOBIOLOGY 81 ( 5 ) 1131 - 1137 2005年9月
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Internal water molecules of light-driven chloride pump proteins
M Shibata, N Muneda, K Ihara, T Sasaki, M Demura, H Kandori
CHEMICAL PHYSICS LETTERS 392 ( 4-6 ) 330 - 333 2004年7月
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Structural Stability of Bacteriorhodopsin Solubilized by Triton X-100
佐々木 貴規, T. Sasaki, M. Sonoyama, Y. Mukai, C. Nakazawa, S. Mitaku
Journal of Photoscience ( 9 ) 293 - 295 2002年
MISC
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Discrimination of Golgi type II membrane proteins focusing on thier membrane spanning peptide sequences
SASAKI Takanori, Masao Yoshizawa, Takanori Sasaki, Yuri Mukai-Ikeda
Proceedings of the 5th International Peptide Symposium 2011年
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Discrimination of GPI-anchored proteins using artificial neural network
佐々木 貴規, Hirotaka Tanaka, Masao Yoshizawa, Takanori Sasaki, Yuri Mukai-Ikeda
Proceedings of the 5th International Peptide Symposium 2011年
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Discrimination of Golgi type II membrane proteins focusing on thier membrane spanning peptide sequences
佐々木 貴規, Masao Yoshizawa, Takanori Sasaki, Yuri Mukai-Ikeda
Proceedings of the 5th International Peptide Symposium 2011年
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Discrimination of GPI-anchored proteins using artificial neural network
SASAKI Takanori, Hirotaka Tanaka, Masao Yoshizawa, Takanori Sasaki, Yuri Mukai-Ikeda
Proceedings of the 5th International Peptide Symposium 2011年
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Development a database of genome-wide GPI-anchored proteins
SASAKI Takanori, H. Takata, T. Konishi, H. Tanaka, M. Yoshizawa, O. Oura, T. Sasaki, Y. Mukai-Ikeda
Proceedings of the 2nd international conference on Trendz in information sciences and computing 110 - 112 2010年
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Development a database of genome-wide GPI-anchored proteins
佐々木 貴規, H. Takata, T. Konishi, H. Tanaka, M. Yoshizawa, O. Oura, T. Sasaki, Y. Mukai-Ikeda
Proceedings of the 2nd international conference on Trendz in information sciences and computing 110 - 112 2010年
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A discrimination method for Golgi type II membrane proteins based on the hydropathy alignment and the position-specific score matrix around their transmembrane regions
Yuri Mukai, Masao Yoshizawa, Hirotaka Tanaka, Takanori Sasaki, Masami Ikeda
Proceedings of the 2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010 82 - 87 2010年
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Identification of mammalian GPI-anchored proteins based on amino acid propensities in their GPI attachment signal sequences
佐々木 貴規, Y. Mukai, O. Oura, T. Sasaki, M. Ikeda
Proceedings of the 2nd international conference on Trendz in information sciences and computing 113 - 117 2010年
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Identification of mammalian GPI-anchored proteins based on amino acid propensities in their GPI attachment signal sequences
SASAKI Takanori, Y. Mukai, O. Oura, T. Sasaki, M. Ikeda
Proceedings of the 2nd international conference on Trendz in information sciences and computing 113 - 117 2010年
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Identification of GPI-anchored proteins using position specific score matrix
Y. Ikeda, O. Oura, T. Sasaki, Y. Yabuki, M. Ikeda
FEBS JOURNAL 276 ( 1 ) 126 - 127 2009年7月
講演・口頭発表等
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ドデシルマルトシドにより可溶化されたファラオニスハロロドプシンが持つカロテノイド結合能
第12回日本蛋白質科学会年会 2012年
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Features of halorhodopsin-carotenoid complex from Natronomonas pharaonis membrane in the solubilized system
37th FEBS Congress 2012年
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Formation of a complex between membrane protein halorhodopsin and carotenoid of bacterioruberin in the solubilized system
The 50th Annual Meeting of the Biophysical Society of Japan 2012年
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Features of halorhodopsin-carotenoid complex from Natronomonas pharaonis membrane in the solubilized system
37th FEBS Congress 2012年
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Formation of a complex between membrane protein halorhodopsin and carotenoid of bacterioruberin in the solubilized system
The 50th Annual Meeting of the Biophysical Society of Japan 2012年
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Correlation between the disaccharide structures of alkyl glycosides and the structural stability of solubilized membrane protein
The 49th Annual Meeting of the Biophysical Society of Japan 2011年
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Correlation between molecular area and solubilizing ability for membrane protein on detergent molecule
Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry 2011年
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ファラオニスハロロドプシンの三量体会合強度に関与するアニオン結合部位の同定
第11回日本蛋白質科学会年会 2011年
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界面活性剤ドデシルマルトシドを用いた膜タンパク質バクテリオロドプシン-脂質間相互作用変化の敏感な検出
第11回日本蛋白質科学会年会 2011年
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逆誤差伝播型ニューラルネットワークによるGPIアンカー型タンパク質の判別方法
第11回日本蛋白質科学会年会 2011年
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Correlation between the disaccharide structures of alkyl glycosides and the structural stability of solubilized membrane protein
The 49th Annual Meeting of the Biophysical Society of Japan 2011年
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Langmuir-Blodgett法による両親媒性ペプチドの構造および配列制御
第72回応用物理学会学術講演会 2011年
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Correlation between molecular area and solubilizing ability for membrane protein on detergent molecule
Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry 2011年
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膜タンパク質バクテリオロドプシンのリガンド結合・解離と非イオン性界面活性剤ドデシルマルトシドに対する可溶性の関係
第10回日本蛋白質科学会年会 2010年
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Trimer formation of N.pharaonis Halorhodopsin is stabilized by the intermolecular interaction among Phe150 residue and leads to functional modulation in detergent solution
14th International Conference on Retinal Proteins 2010年
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Correlation between tertiary structure and solubility in Dodecyl-β-D-maltoside on membrane protein bacteriorhodopsin
The 48th Annual Meeting of the Biophysical Society of Japan 2010年
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Detection of the ligand binding/release state of membrane protein bacteriorhodopsin by the change of solubility in Dodecyl-β-D-maltoside
35th FEBS Congress 2010年
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Trimer formation of N.pharaonis Halorhodopsin is stabilized by the intermolecular interaction among Phe150 residue and leads to functional modulation in detergent solution
14th International Conference on Retinal Proteins 2010年
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Correlation between tertiary structure and solubility in Dodecyl-β-D-maltoside on membrane protein bacteriorhodopsin
The 48th Annual Meeting of the Biophysical Society of Japan 2010年
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Detection of the ligand binding/release state of membrane protein bacteriorhodopsin by the change of solubility in Dodecyl-β-D-maltoside
35th FEBS Congress 2010年
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Computational detection of GPI-anchored proteins using hydropathy profile and PSSM
EUROCARB 2009 (15th European Carbohydrate Symposium) 2009年
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Stabilization of trimeric assembly of halorhodopsin, NpHR by C3-symmetric geometry among F150 aromatic rings
The 47th Annual Meeting of the Biophysical Society of Japan 2009年
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Identification of GPI-anchored proteins using position specific score matrix
34th FEBS Congress 2009年
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Stabilization of trimeric assembly of halorhodopsin, NpHR by C3-symmetric geometry among F150 aromatic rings
The 47th Annual Meeting of the Biophysical Society of Japan 2009年
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Computational detection of GPI-anchored proteins using hydropathy profile and PSSM
EUROCARB 2009 (15th European Carbohydrate Symposium) 2009年
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Identification of GPI-anchored proteins using position specific score matrix
34th FEBS Congress 2009年
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Is the photoactivity of halorhodopsin modulated by the assembly of homotrimer ?
The 46th Annual Meeting of the Biophysical Society of Japan 2008年
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Trimer assembly of Natronomonas Pharaonis halorhodopsin, NphR in lipid bilayer and detergent
13th International Conference on Retinal Proteins 2008年
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Is the photoactivity of halorhodopsin modulated by the assembly of homotrimer ?
The 46th Annual Meeting of the Biophysical Society of Japan 2008年
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Trimer assembly of Natronomonas Pharaonis halorhodopsin, NphR in lipid bilayer and detergent
13th International Conference on Retinal Proteins 2008年
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Visual spectral shift of halorhodopsin in pH titration
9th Hokkaido University-Seoul National University Joint Symposium Satellite Session 2007年
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The change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion
9th Hokkaido University-Seoul National University Joint Symposium Satellite Session 2007年
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Visual spectral shift of halorhodopsin in pH titration
9th Hokkaido University-Seoul National University Joint Symposium Satellite Session 2007年
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The change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion
9th Hokkaido University-Seoul National University Joint Symposium Satellite Session 2007年
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膜タンパク質ハロロドプシンはなぜトリマー形成するのか？
日本生物物理学会北海道支部例会 2006年
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The Change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
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Trimer-monomer conversion of pharaonis halorhodopsin by anion binding
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
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Structural network in the extracellular region corresponding to the visual spectral shift of halorhodopsin
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
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The role of E234 on the extracellular site in the anion pump of pharaonis halorhodopsin
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ). Okinawa Convention Center, Okinawa, Japan 2006年
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Effects of EC-channel residues, E234 and R176, of pharaonis halorhodopsin on structural stability and functions
12th International Conference on Retinal Proteins (12/ ICPR) 2006年
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Functional and structural role of trimer paking of pharaonis halorhodopsin,
12th International Conference on Retinal Proteins (12/ICPR) 2006年
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Inversion of spectral shifts of pharaonis halorhodopsin in anion titration caused by changing pH
12th International Conference on Retinal Proteins (12/ ICPR) 2006年
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古細菌ロドプシンの吸収波長シフト方向を決定する構造因子
第6回蛋白質科学会年会 2006年
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Functional and structural role of trimer paking of pharaonis halorhodopsin,
12th International Conference on Retinal Proteins (12/ICPR) 2006年
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Inversion of spectral shifts of pharaonis halorhodopsin in anion titration caused by changing pH
12th International Conference on Retinal Proteins (12/ ICPR) 2006年
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Effects of EC-channel residues, E234 and R176, of pharaonis halorhodopsin on structural stability and functions
12th International Conference on Retinal Proteins (12/ ICPR) 2006年
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The Change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
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Trimer-monomer conversion of pharaonis halorhodopsin by anion binding
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
-
Structural network in the extracellular region corresponding to the visual spectral shift of halorhodopsin
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ) 2006年
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The role of E234 on the extracellular site in the anion pump of pharaonis halorhodopsin
Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ). Okinawa Convention Center, Okinawa, Japan 2006年
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プロトンをポンプするアジド結合型ハロロドプシンの低温赤外分光
日本生物物理学会 第43回日本生物物理学会年会 2005年
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膜タンパク質ハロロドプシンのアニオン結合と自己組織化構造
北海道21世紀COEプログラム「バイオとナノを融合する新生命科学拠点」第六回 COE大学院生主催研究発表会 2005年
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ファラオニスハロロドプシンのアニオン結合と集積構造形成
分子科学研究所研究会「ロドプシンの仲間・Ｇ蛋白質共役型レセプターの機能と構造 2005年
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脱塩状態における膜タンパク質ハロロドプシンの退色と集積構造崩壊
日本蛋白質科学会 第5回日本蛋白質科学会年会 2005年
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膜タンパク質ハロロドプシンのオリゴマー構造形成メカニズム
特定領域研究「生体超分子の構造形成と機能制御の原子機構」第一回ワークショップ 2005年
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The correlation between anion binding and the mechanism of oligomer formation for membrane protein halorhodopsin
日本生物物理学会 第43回日本生物物理学会年会 2005年
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Chloride ion promotes Retinal binding to halo-opsin in Triton X-100
The 1st Pacific-Rim International Conference on Protein Science (PRICP) 2004年
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Chloride ion promotes Retinal binding to halo-opsin in Triton X-100
The 1st Pacific-Rim International Conference on Protein Science (PRICP) 2004年
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光駆動塩素イオンポンプ蛋白質、ハロロドプシン(HR)中の内部結合水の構造解析
第31回生体分子化学討論会 2004年
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界面活性剤Triton X-100がファラオニスハロロドプシンのシッフ塩基結合、2次元結晶構造に与える影響に関して
第42回日本生物物理学会年会 2004年
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界面活性剤Triton X-100による可溶化バクテリオロドプシンの構造安定性について
第3回日本蛋白質科学会年会 2003年
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界面活性剤Triton X-100による可溶化バクテリオロドプシンの構造安定性
特定領域研究Ｃ「ゲノム情報科学の進展開」公開シンポジウム 2002年
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Structural stability of bacteriorhodopsin solubilized by Triton X-100
1st Asian Conference on Photobiology 2002年
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Triton X-100による可溶化バクテリオロドプシンの光誘起変性
第40回日本生物物理学会年会 2002年
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Structural stability of bacteriorhodopsin solubilized by Triton X-100
1st Asian Conference on Photobiology 2002年
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可視領域におけるバクテリオロドプシンのCDスペクトルが示す多様性
第6回日本光生物学協会講演会 1999年
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バクテリオロドプシンの立体構造安定性における二次元結晶構造の効果-Ⅱ. オクチルグルコシド、ドデシルマルトシド、Triton X-100 による可溶化の比較
第11回日本蛋白質工学会年会 1999年
Works（作品等）
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固体ＮＭＲスペクトルの信号帰属自動化アルゴリズム開発
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膜蛋白質古細菌ロドプシンの物性調査
受賞
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財団法人北海道大学クラーク記念財団博士課程在学生研究助成
2006年
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