Updated on 2026/03/07

写真a

 
KAWAGUCHI MAIKO
 
Organization
Undergraduate School School of Agriculture Professor
Title
Professor
External link

Degree

  • PhD ( 2001.3   Yokohama City University )

Research Interests

  • animal welfare

  • behavior

  • neuroendocrine

  • environmental factor

  • developmental disorder

  • 神経内分泌

  • 環境因子

  • 発達障害

  • animal welfare

  • behavior

Research Areas

  • Life sciences / Animal production science

  • Life sciences / Laboratory animal science

  • Environmental science/Agricultural science / Environmental impact assessment

  • Life sciences / Animals: biochemistry, physiology, behavioral science

Education

  • Yokohama City University   Graduate School, Division of Medicine

    1997.4 - 2001.3

      More details

    Country/Region: Japan

    researchmap

  • Tokyo University of Agriculture and Technology   Faculty of Agriculture   Department of Veterinary Medicine

    1991.4 - 1997.3

      More details

    Country/Region: Japan

    researchmap

Research History

  • Meiji University   School of Agriculture   Professor

    2025.10

      More details

    Country/Region:Japan

    researchmap

  • Meiji University   School of Agriculture   Associate Professor

    2019.4 - 2025.9

      More details

  • Meiji University School of Agriculture Senior Assistant Professor

    2011.4 - 2019.3

      More details

  • Musashino University   Lecturer

    2010.4 - 2011.3

      More details

  • Musashino University   Assistant professor

    2008.5 - 2010.3

      More details

  • Musashino University   助手

    2005.5 - 2008.4

      More details

  • Johns Hopkins University   School of Medicine

    2002.12 - 2004.3

      More details

    Country/Region:United States

    researchmap

  • National Institute for Environmental Studies

    2001.4 - 2002.12

      More details

▼display all

Papers

  • Effect of introducing boat fenders on the regurgitation behavior of captive common bottlenose dolphins (Tursiops truncatus) Reviewed

    Effect of introducing boat fenders on the regurgitation behavior of captive common bottlenose dolphins (Tursiops truncatus)

    65 ( 2 )   129 - 134   2025.8

     More details

    Authorship:Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    researchmap

  • Candidate Anxiety‐Related Genes in the Hippocampus of Hatano Male Rats: Anxiolytic Action of Neuromedin U in the Hippocampus Reviewed

    Kaito Sato, Atsuhiro Ishii, Shohei Kobayashi, Taichi Hatakeyama, Gen Watanabe, Tomoko Soga, Ishwar Parhar, Takashi Matsuwaki, Shogo Moriya, Ryo Ohta, Shuichi Chiba, Maiko Kawaguchi

    Neuropsychopharmacology Reports   45 ( 2 )   2025.4

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    ABSTRACT

    Identifying genes involved in anxiety is important to elucidate the mechanisms of anxiety disorders. Hatano high avoidance animals (HAA) and low avoidance animals (LAA) are inbred strains that are selected based on their performance in an active avoidance test. HAA shows a higher level of anxiety‐like behavior than LAA. The present study focuses on the hippocampus, which is associated with anxiety‐like behavior, and used microarray analysis and RT‐qPCR to select genes with differential expression in the hippocampus between HAA and LAA (Experiment 1). The microarray analysis revealed differences in 498 gene expressions between HAA and LAA, of which 21 genes were ligand‐receptor related in the nervous system. We selected nine genes based on p value and conducted RT‐qPCR, which identified seven genes whose expressions were higher in LAA than in HAA. We focused on the gene, neuromedin U receptor 2 (Nmur2), which showed significantly different expression levels between HAA and LAA. Further, we conducted a behavioral test to evaluate anxiety levels by administering neuromedin U (NmU), an agonist for NmUR2, into the hippocampus (Experiment 2). NmU treatment did not affect the results of the open field test or the elevated plus maze test, which are unconditioned response models of anxiety. However, in the passive avoidance test, a conditioned response model of anxiety, the NmU group showed less anxiety‐like behavior than the control group. This is the first study to show that NmU suppresses the conditioned response model of anxiety via the hippocampus, indicating that NmUR2 in the hippocampus may be involved in anxiety‐like behavior.

    DOI: 10.1002/npr2.70018

    researchmap

  • Administration of a Selective Antagonist for Pituitary Adenylate Cyclase‐Activating Polypeptide Receptor in the Hippocampus Causes Anxiolytic Effects in the Male Rat Reviewed

    Kaito Sato, Shuichi Chiba, Taichi Hatakeyama, Takashi Matsuwaki, Gen Watanabe, Maiko Kawaguchi

    Neuropsychopharmacology Reports   45 ( 1 )   2024.12

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    ABSTRACT

    Pituitary adenylate cyclase‐activating polypeptide (PACAP) affects rodents' stress‐related behaviors, such as anxiety‐like behavior or fear conditioning. However, previous studies have investigated the effect of intracerebroventricular, but not hippocampal, injection of this PAC1R‐selective antagonist (PACAP‐6‐38) on anxiety‐like behavior. However, it has been reported that administration of PACAP‐6‐38 to the dorsal hippocampus reduces the fear response in a fear conditioning test. Therefore, this study aimed to determine whether the effect of dorsal hippocampal PACAP‐6‐38 injection in Sprague–Dawley rats can affect anxiety‐like behavior assessed by an elevated plus‐maze test. As a result, rats treated with PACAP‐6‐38 spent longer time in open arms than those with saline, suggesting that this drug has an anxiolytic effect. In conclusion, the role of PACAP in the dorsal hippocampus can promote anxiety‐like behavior.

    DOI: 10.1002/npr2.12514

    researchmap

  • 非定常状態における化学物質曝露の健康リスク評価手法の基礎的検討 Reviewed

    川口真以子, 柳澤利枝, 小池英子, 鈴木規之

    地球環境   28 ( 2 )   147 - 154   2023.3

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:国際環境研究協会  

    researchmap

  • Bidirectional effects of voluntary exercise on the expression of <i>Bdnf</i> isoforms in the hippocampus of Hatano rat strains displaying different activity levels Reviewed

    Shuichi Chiba, Hikaru Asano, Shogo Moriya, Taichi Hatakeyama, Shohei Kobayashi, Ryo Ohta, Maiko Kawaguchi

    Neuropsychopharmacology Reports   43 ( 1 )   126 - 131   2023.1

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    DOI: 10.1002/npr2.12313

    researchmap

    Other Link: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/npr2.12313

  • Toxicological effects of Tris (1,3-dichloro-2-propyl) phosphate exposure in adult male rats differ depending on the history of exposure in the neonatal period Reviewed International journal

    Takahiro Akimoto, Shohei Kobayashi, Airi Nakayama, Anna Isobe, Koudai Abe, Taichi Hatakeyama, Ryo Ohta, Rie Yanagisawa, Eiko Koike, Noriyuki Suzuki, Maiko Kawaguchi

    Journal of applied toxicology   42 ( 9 )   1503 - 1509   2022.9

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:John Wiley & Sons  

    researchmap

  • Possible effects of voluntary exercise intensity on anxiety-like behavior and its underlying molecular mechanisms in the hippocampus: Results from a study in Hatano rats. Reviewed International journal

    Hikaru Asano, Shogo Moriya, Taichi Hatakeyama, Shohei Kobayashi, Takahiro Akimoto, Ryo Ohta, Maiko Kawaguchi

    Behavioural Brain Research   427   113854 - 113854   2022.6

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier  

    researchmap

  • Alterations between high and low-avoidance lines of Hatano rats in learning behaviors, ultrasonic vocalizations, and histological characteristics in hippocampus and amygdala Reviewed

    Shuichi Chiba, Toru Okawara, Kotaro Kawakami, Ryo Ohta, Maiko Kawaguchi

    Physiology & Behavior   245   113670 - 113670   2022.3

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier {BV}  

    DOI: 10.1016/j.physbeh.2021.113670

    researchmap

  • Effects of tris(1,3-dichloro-2-propyl) phosphate on epididymal sperm parameters in adult male rats Reviewed

    Shohei KOBAYASHI, Natsuko KAWANO, Kenji MIYADO, Ryo OHTA, Takahiro AKIMOTO, Taichi HATAKEYAMA, Maiko KAWAGUCHI

    Journal of Veterinary Medical Science   84 ( 1 )   153 - 156   2021.12

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japanese Society of Veterinary Science  

    Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is widely used as a flame retardant and is known to exhibit anti-androgenic effects in vitro and in vivo. To assess the reproductive toxicity potency of TDCIPP, we investigated the effects of 7 days of TDCIPP oral administration on epididymal sperm motion and concentration in adult male Wistar-Imamichi rats. Thirty-five days after the final administration, sperm parameters were evaluated by computer-assisted sperm analysis. Results showed that sperm swimming progression and vigor and sperm concentration in TDCIPP-treated rats were unexpectedly higher than those in control rats. TDCIPP did not significantly affect the percentage of motile sperms or sperm swimming pattern. These results contribute to the understanding of the biological effects of TDCIPP.

    DOI: 10.1292/jvms.21-0046

    PubMed

    researchmap

  • Impact of dietary exposure to low-dose tris(1,3-dichloro-2-propyl)phosphate in allergic asthmatic mice Reviewed

    Rie Yanagisawa, Eiko Koike, Tin-Tin Win-Shwe, Maiko Kawaguchi, Hirohisa Takano

    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY   1 - 12   2021.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/08923973.2021.1959609

    researchmap

  • Novel toxicity of tris (1,3-dichloro-2-propyl) phisphate in adult male rats. Reviewed International journal

    Shohei Kobayashi, Kodai Abe, Anna Isobe, Airi Nakayama, Takahiro Akimoto, Taichi Hatakeyama, Yoshiaki Saito, Rie Yanagisawa, Eiko Koike, Noriyuki Suzuki, Maiko Kawaguchi, Ryo Ohta

    Journal of Applied Toxicology   41 ( 6 )   987 - 992   2021.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:John Wiley & Sons, Ltd.  

    researchmap

  • Maternal traits during lactation period reduce the anxiety-related behavior in male offspring: Results from a fostering study in Hatano rats Reviewed International journal

    Horii Y, Nakajima S, Akieda-Asai S, Ohta R, Kawaguchi M

    Physiology & Behavior   229   2021.2

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Investigating the effects of nest shading on the green turtle (Chelonia mydas) hatchling phenotype in the Ogasawara islands using a field-based split clutch experiment Reviewed International journal

    Shohei Kobayashi, Daisuke Endo, Satomi Kondo, Chiyo Kitayama, Ryuta Ogawa, Katsuhiko Arai, Gen Watanabe, Maiko Kawaguchi

    Journal of Experimental Zoology Part A: Ecological and Integrative Physiology   333 ( 9 )   629 - 636   2020.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    researchmap

  • Repressor Element 1 Silencing Transcription factor /Neuron-Restrictive Silencing Factor (REST/NRSF) in Social Stress and Depression Reviewed International journal

    Soga T, Nakajima S, Kawaguchi M, Parhar IS.

    Prog Neuropsychopharmacol Biol Psychiatry   2020.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • The impact of oral exposure to low dose tris(2-butoxyethyl)phosphate in allergic asthmatic mice Reviewed

    Yanagisawa R, Koike E, Win-Shwe TT, Kawaguchi M, Takano H

    Journal of Applied Toxicology   2020.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • The effects of 28-day early-life exposure to triphenyl phosphate (TPhP) on odor preference and sexual behavior in female rats Reviewed

    Airi Nakayama, Tatsuya Hattori, Anna Isobe, Shohei Kobayashi, Go Suzuki, Hidetaka Takigami, Maiko Kawaguchi

    Journal of Applied Toxicology   2020.6

     More details

    Authorship:Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jat.4021

    Scopus

    PubMed

    researchmap

  • Relationship between motor function and ultrasonic vocalizations induced by maternal separation in rat pups. Reviewed

    Isobe, A. and Kawaguchi, M.

    The Journal of Veterinary Medical Science   81 ( 2 )   287 - 293   2019.2

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japanese Society of Veterinary Science  

    DOI: 10.1292/jvms.18-0604

    Scopus

    PubMed

    researchmap

  • Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat Reviewed

    Anna ISOBE, Tsutomu SHIMADA, Masaki ABURADA, Rie YANAGISAWA, Tomoyoshi SAKAWA, Takahiro NAKAMURA, Toshiyuki HIMI, Ryo OHTA, Maiko KAWAGUCHI

    The Journal of Veterinary Medical Science   81 ( 1 )   147 - 154   2019.1

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test Reviewed International journal

    Horii Y, McTaggart, Kawaguchi M

    JoVE   29 ( 136 )   2018.6

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Journal of Visualized Experiments,  

    researchmap

  • Male Hatano low-avoidance rats show more active sexual behavior with lower plasma testosterone than high-avoidance rats Reviewed

    Nakayama A, Okawa H, Zheng M, Pu S, Watanabe G, Ohta R, Kawaguchi M

    J Vet Med Sci.   80 ( 7 )   1179 - 1182   2018.5

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japanese Society for Veterinary Sciences  

    researchmap

  • Early-life exposure to Tris(1,3-dichloroisopropyl) phosphate induces dose-dependent suppression of sexual behavior in male rats. Reviewed International journal

    Manami Kamishima, Tatsuya Hattori, Go Suzuki, Hidenori Matsukami, Chiaki Komine, Yasuyuki Horii, Gen Watanabe, Takumi Oti, Hirotaka Sakamoto, Tomoko Soga, Ishwar S Parhar, Yasuhiko Kondo, Hidetaka Takigami, Maiko Kawaguchi

    Journal of applied toxicology : JAT   38 ( 5 )   649 - 655   2018.5

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:John Wiley & Sons  

    Exposure to endocrine-disrupting chemicals may adversely affect animals, particularly during development. Tris(1,3-dichloroisopropyl) phosphate (TDCIPP) is an organophosphate with anti-androgen function in vitro that is present in indoor dust at relatively high concentrations. In male rats, androgens are necessary for the development of reproductive organs, as well as the endocrine and central nervous systems. However, we currently do not know the exact effects of TDCIPP exposure through suckling on subsequent reproductive behavior in males. Here, we show that TDCIPP exposure (25-250 mg kg-1 via oral administration over 28 consecutive days post-birth) suppressed male sexual behavior and reduced testes size. These changes were dose-dependent and appeared first in adults rather than in juveniles. These results demonstrate that TDCIPP exposure led to normal body growth and appearance in juveniles, but disrupted the endocrine system and physiology in adults. Therefore, assays should be performed using adult animals to ensure accuracy, and to confirm the influence of chemical substances given during early mammalian life.

    DOI: 10.1002/jat.3569

    PubMed

    researchmap

  • Effects of neonatal 17α-ethinyloestradiol exposure on female-paced mating behaviour in the rat. Reviewed International journal

    Komine C, Nakajima S, Kondo Y, Horii Y, Yoshida M, Kawaguchi M.

    J Appl Toxicol.   37 ( 8 )   996 - 1003   2017.2

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:John Wiley & Sons  

    researchmap

  • A Single Neonatal Injection of Ethinyl Estradiol Impairs Passive Avoidance Learning and Reduces Expression of Estrogen Receptor a in the Hippocampus and Cortex of Adult Female Rats Reviewed

    Tatsuomi Shiga, Takahiro J. Nakamura, Chiaki Komine, Yoshikuni Goto, Yasushi Mizoguchi, Midori Yoshida, Yasuhiko Kondo, Maiko Kawaguchi

    PLOS ONE   11 ( 1 )   2016.1

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0146136

    Web of Science

    researchmap

  • Higher detection sensitivity of anxiolytic effects of diazepam by ledge-free open arm with opaque walled closed arm elevated plus maze in male rats Reviewed

    Yasuyuki Horii, Maiko Kawaguchi

    BEHAVIOURAL BRAIN RESEARCH   294 ( Nov 1 )   131 - 140   2015.11

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbr.2015.07.059

    Web of Science

    researchmap

  • Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice Reviewed

    Shotaro Kamata, Junya Yamamoto, Kenta Kamijo, Takahito Ochiai, Tamako Morita, Yurika Yoshitomi, Yoshifumi Hagiya, Masashi Kubota, Rika Ohkubo, Maiko Kawaguchi, Toshiyuki Himi, Tadashi Kasahara, Isao Ishii

    MOLECULAR NUTRITION & FOOD RESEARCH   58 ( 6 )   1309 - 1321   2014.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/mnfr.201300758

    Web of Science

    researchmap

  • Male Hatano High-Avoidance Rats Show High Avoidance and High Anxiety-Like Behaviors as Compared with Male Low-Avoidance Rats Reviewed

    Yasuyuki Horii, Maiko Kawaguchi, Ryo Ohta, Akihiro Hirano, Gen Watanabe, Nobumasa Kato, Toshiyuki Himi, Kazuyoshi Taya

    EXPERIMENTAL ANIMALS   61 ( 5 )   517 - 524   2012.10

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.61.517

    Web of Science

    Scopus

    PubMed

    researchmap

  • Maternal Exposure to Isobutyl-Paraben Impairs Social Recognition in Adult Female Rats Reviewed

    Maiko Kawaguchi, Kaori Morohoshi, Hideki Imai, Masatoshi Morita, Nobumasa Kato, Toshiyuki Himi

    EXPERIMENTAL ANIMALS   59 ( 5 )   631 - 635   2010.10

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.59.631

    Web of Science

    researchmap

  • Maternal isobutyl-paraben exposure alters anxiety and passive avoidance test performance in adult male rats Reviewed

    Maiko Kawaguchi, Kaoru Irie, Kaori Morohoshi, Gen Watanabe, Kazuyoshi Taya, Masatoshi Morita, Yasuhiko Kondo, Hideki Imai, Toshiyuki Himi

    NEUROSCIENCE RESEARCH   65 ( 2 )   136 - 140   2009.10

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neures.2009.06.011

    Web of Science

    researchmap

  • Maternal Isobutyl-Paraben Exposure decreases the Plasma Corticosterone Level in Dams and Sensitivity to Estrogen in Female Offspring Rats Reviewed

    Maiko Kawaguchi, Kaori Morohoshi, Junya Masuda, Gen Watanabe, Masatoshi Morita, Hideki Imai, Kazuyoshi Taya, Toshiyuki Himi

    JOURNAL OF VETERINARY MEDICAL SCIENCE   71 ( 8 )   1027 - 1033   2009.8

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.71.1027

    Web of Science

    researchmap

  • Cardiotonic effect of Apocynum venetum L. extracts on isolated guinea pig atrium Reviewed

    Kaoru Irie, Takahiro Sato, Ippei Tanaka, Jun-ichiro Nakajima, Maiko Kawaguchi, Toshiyuki Himi

    JOURNAL OF NATURAL MEDICINES   63 ( 2 )   111 - 116   2009.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11418-008-0296-2

    Web of Science

    researchmap

  • Expression of Nerve Growth Factor and its Receptors trkA and p75 and Inhibin alpha-Subunit in the Ovarian Interstitial Cells of Lactating Golden Hamsters Reviewed

    Qiang Weng, Zhanquan Shi, Maiko Kawaguchi, Gen Watanabe, Kazuyoshi Taya

    JOURNAL OF REPRODUCTION AND DEVELOPMENT   54 ( 5 )   397 - 401   2008.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.20031

    Web of Science

    researchmap

  • Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor beta 1 and synapsin I in brain, resulting in thyroid function vulnerability in rats Reviewed

    Maiko Kawaguchi, Kaori Morohoshi, Erina Saita, Rie Yanagisawa, Gen Watanabe, Hirohisa Takano, Masatoshi Morita, Hideki Imai, Kazuyoshi Taya, Toshiyuki Himi

    ENDOCRINE   33 ( 3 )   277 - 284   2008.6

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12020-008-9086-6

    Web of Science

    researchmap

  • Bisphenol A induces transforming growth factor-beta 3 mRNA in the preoptic area: A cDNA expression array and Northern blot study Reviewed

    Atsushi Fukushima, Toshiya Funabashi, Maiko Kawaguchi, Dai Mitsushima, Fukuko Kimura

    NEUROSCIENCE LETTERS   411 ( 1 )   81 - 85   2007.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2006.10.010

    Web of Science

    researchmap

  • Effects of bilateral efferent duct ligation on sperm motility and secretion of FSH, LH, inhibin, and testosterone in adult male rats Reviewed

    Longquan Ren, Mohamed S. Medan, Chunmei Li, Qiang Weng, Maiko Kawaguchi, Gen Watanabe, Kazuyoshi Taya

    ENDOCRINE   30 ( 2 )   151 - 160   2006.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1385/ENDO:30:2:151

    Web of Science

    researchmap

  • Effects of p-nonylphenol and 4-tert-octylphenol on the anterior pituitary functions in adult ovariectomized rats Reviewed

    Miyako Furuta, Toshiya Funabashi, Maiko Kawaguchi, Takahiro J. Nakamura, Dai Mitsushima, Fukuko Kimura

    NEUROENDOCRINOLOGY   84 ( 1 )   14 - 20   2006

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000096093

    Web of Science

    researchmap

  • Induction of superovulation by immunoneutralization of endogenous inhibin in immature rats. Reviewed

    Harumichi Ishigame, Mohamed S Medan, Maiko Kawaguchi, Atsushi Fukuda, Gen Watanabe, Koji Y Arai, Kazuyoshi Taya

    The Journal of reproduction and development   51 ( 5 )   559 - 566   2005.10

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    The effects of passive immunoneutralization of endogenous inhibin on ovulation rate in immature rats were investigated. Efficiency of superovulation on production of fertilized oocytes was compared between the inhibin antiserum (inhibin-AS) and equine chorionic gonadotropin (eCG) protocols. Immature female Wistar strain rats were superovulated with a single injection of 100-200 microl inhibin-AS, with and without an injection of human chorionic gonadotropin (hCG). A total of 77.8% of the 26-30-day-old rats treated with a single injection of 100-200 microl inhibin-AS ovulated 72 h after treatment, while rats given normal goat serum (NGS; 200 microl) did not ovulate. At 28 days of age, all of the inhibin-AS treated rats ovulated when additional hCG treatment was given, whereas the number of ovulated oocytes was not affected. The number of ovulated oocytes in the inhibin-AS-hCG treated groups was significantly higher than that of the NGS-hCG treated group. In addition, plasma concentrations of FSH in the inhibin-AS-hCG treated group significantly increased compared with the NGS treated group. While the percentage of mated rats in the 200 microl inhibin-AS-hCG treated group was significantly lower than that of the 15 IU eCG-hCG treated group, the fertilization rate was comparable between the two groups. The number of fertilized oocytes in the 200 microl inhibin-AS-hCG treated group was significantly higher in comparison with the 15 IU eCG-hCG treated group. These results suggest that immunoneutralization of endogenous inhibin could be a reliable method for induction of superovulation to collect a large number of normally fertilized oocytes in immature rats.

    PubMed

    researchmap

  • Expression of Nerve Growth Factor(NGF), and Its Receptors TrkA and p75 in the Reproductive Organs of the Adult Male Rats(Reproductive Biology) : Reviewed

    Li ChunMei, Watanabe Gen, Weng Qiang, Jin WanZhu, Furuta Chie, Suzuki Akira K., Kawaguchi Maiko, Taya Kazuyoshi

    Zoological science   22 ( 8 )   933 - 937   2005.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Zoological Society of Japan  

    Immunolocalization of nerve growth factor (NGF) and its receptors, TrkA and p75 in the reproductive organs of adult male rats was investigated. Sections of the testis, efferent duct, epididymis, deferent duct, seminal vesicle, coagulating gland and prostate of adult male rats were immunostained by the avidin-biotin-peroxidase complex methods (ABC). NGF was expressed in Leydig cells, primary spermatocytes and pachytene spermatocytes in the testis. TrkA only immunoreacted to elongate spermatids and p75 showed positive immunostaining in the Sertoli cells, Leydig cells, the pachytene spermatocytes and elongate spermatids. Immunoreactions for NGF and its two receptors were detected in epithelial cells of efferent duct, deferent duct and epididymis. In addition, immunoreactions for NGF and its two receptors were also observed in columnar secretory epithelium lines of the seminal vesicles, prostate and coagulating gland. These results suggest that NGF is an important growth factor in gonadal function of adult male rats.

    DOI: 10.2108/zsj.22.933

    CiNii Research

    researchmap

    Other Link: http://dl.ndl.go.jp/info:ndljp/pid/10867806

  • Dorsomedial hypothalamic corticotropin-releasing factor mediation of exercise-induced anorexia Reviewed

    M Kawaguchi, KA Scott, TH Moran, S Bi

    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY   288 ( 6 )   R1800 - R1805   2005.6

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpregu.00805.2004.

    Web of Science

    researchmap

  • Exposure to bisphenol A during gestation and lactation causes loss of sex difference in corticotropin-releasing hormone-immunoreactive neurons in the bed nucleus of the stria terminalis of rats Reviewed

    T Funabashi, M Kawaguchi, M Furuta, A Fukushima, F Kimura

    PSYCHONEUROENDOCRINOLOGY   29 ( 4 )   475 - 485   2004.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0306-4530(03)00055-6

    Web of Science

    researchmap

  • Butyl benzyl phthalate, an endocrine disrupter, inhibits pulsatile luteinizing hormone secretion under an insulin-induced hypoglycaemic state in ovariectomized rats Reviewed

    M Kawaguchi, T Funabashi, S Aiba, F Kimura

    JOURNAL OF NEUROENDOCRINOLOGY   14 ( 6 )   486 - 491   2002.6

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1046/j.1365-2826.2002.00804.x

    Web of Science

    researchmap

  • 内分泌かく乱物質の中枢作用: プロジェステロン受容体を指標として

    舩橋敏也, 佐野亜加根, 美津島大, 中村孝博, 川口真以子, 貴邑冨久子

    環境ホルモン研究報告 平成13年度[報告書第4号]   2002.6

     More details

    Language:Japanese   Publisher:横浜市立大学  

    researchmap

  • The endocrine disrupters butyl benzyl phthalate and bisphenol A increase the expression of progesterone receptor messenger ribonucleic acid in the preoptic area of adult ovariectomized rats Reviewed

    T Funabashi, M Kawaguchi, F Kimura

    NEUROENDOCRINOLOGY   74 ( 2 )   77 - 81   2001.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000054672

    Web of Science

    researchmap

  • 内分泌かく乱物質の中枢作用

    川口真以子, 舩橋利也, 貴邑冨久子

    環境ホルモン共同研究プロジェクト平成12年度報告書   2001.6

     More details

    Language:Japanese   Publisher:横浜市立大学  

    researchmap

  • Effects of gestational and lactational exposure to bisphenol a on the hypothalamic control mechanism of reproduction in female rats Reviewed

    Maiko Kawaguchi Toshiya Funabashi, Dai Mitsushima and Fukuko

    52 ( 2 )   115 - 126   2001.3

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    researchmap

  • 内分泌攪乱物質の中枢作用に関する神経内分泌学的検討

    横浜市立大学 横大院   ( 550 )   2001.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    (博士学位論文)

    researchmap

  • 脳を攻撃する環境ホルモン

    貴邑冨久子, 川口真以子ほ

    環境ホルモン-文明・社会・生命   ( Vol.2 )   189-193   2001.2

     More details

    Language:Japanese  

    researchmap

  • 胎仔期及び授乳期におけるBisphenol A曝露のラット生殖内分泌機能におよぼす影響

    川口真以子, 舩橋利也, 貴邑冨久子

    環境ホルモン共同研究プロジェクト平成11年度報告書   2000.6

     More details

    Language:Japanese   Publisher:横浜市立大学  

    researchmap

  • Menstrual changes in sleep, rectal temperature and melatonin rhythms in a subject with premenstrual syndrome Reviewed

    SHINOHARA K

    Neurosci. Lett.   281 ( 2-3 )   159 - 162   2000.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    CiNii Research

    researchmap

  • 成熟ラット内分泌機能に対する内分泌撹乱物質の影響

    川口真以子, 舩橋利也, 貴邑冨久子

    環境ホルモン共同研究プロジェクト平成10年度報告書   7 - 10   1999.6

     More details

    Language:Japanese  

    researchmap

  • Intravenous injections of nicotine decrease the pulsatile secretion of LH by inhibiting the gonadotropin-releasing hormone (GnRH) pulse generator activity in female rats Reviewed

    A Sano, T Funabashi, M Kawaguchi, K Shinohara, F Kimura

    PSYCHONEUROENDOCRINOLOGY   24 ( 4 )   397 - 407   1999.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0306-4530(98)00089-4

    Web of Science

    researchmap

  • Intravenous injections of nicotine decrease the pulsatile secretion of LH by inhibiting the gonadotropin-releasing hormone (GnRH) pulse generator activity in female rats. Reviewed International journal

    Akane Sano, Toshiya Funabashi, Maiko Kawaguchi, Kazuyuki Shinohara and Fukuko Kimura

    Psychoneuroendocrinology   24 ( 4 )   397 - 407   1999.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    researchmap

  • Insulin-induced hypoglycemia does not impair the surge of luteinizing hormone secretion in the proestrous rat Reviewed

    M Kawaguchi, T Funabashi, F Kimura

    NEUROSCIENCE LETTERS   256 ( 3 )   131 - 134   1998.11

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0304-3940(98)00783-6

    Web of Science

    researchmap

▼display all

Books

  • 脳を攻撃する環境ホルモン

    貴邑冨久子, 舩橋利也, 川口真以子( Role: Joint author)

    藤原書店  2001.2 

     More details

    Responsible for pages:189-193   Language:Japanese  

    researchmap

MISC

  • 飼育バンドウイルカ(Tursiops truncatus)に対するボートフェンダー投入による吐き戻し行動抑制効果の持続性と糞中コルチゾール濃度の推移

    岩田汐央・白形知佳・羽田秀人・長野翔平・渡辺元・川口真以子

    74   1 - 12   2025

     More details

    Authorship:Corresponding author   Language:Japanese  

    researchmap

  • 幼若期tris(1,3-dichloroisopropyl)phosphate(TDCIPP)とtriphenyl phosphate(TPhP)曝露は雄ラットの性行動へ濃度依存的な抑制効果をもつ

    服部達哉, 神島愛未, 鈴木剛, 松神秀徳, 渡辺元, 近藤保彦, 滝上英孝, 川口真以子

    環境ホルモン学会研究発表会プログラム・要旨集   19th   2016

  • Behavioral profile in ovariectomized female Hatano high- and low-avoidance rats

    Maiko Kawaguchi, Ryo Ohta, Hiroko Makihara, Gen Watanabe, Kazuyoshi Taya, Tsutomu Shimada, Masaki Aburata, Nobumasa Kato, Toshiyuki Himi

    ENDOCRINE JOURNAL   57   S527 - S527   2010.3

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    Web of Science

    researchmap

  • Behavioral profiles of HATANO rats

    Toshiyuki Himi, Maiko Kawaguchi, Kaori Morohoshi, Gen Watanabe, Kazuyoshi Taya, Masatoshi Morita, Yasuhiko Kondo, Hideki Imai, Nobumasa Kato

    NEUROSCIENCE RESEARCH   68   E204 - E204   2010

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    DOI: 10.1016/j.neures.2010.07.2476

    Web of Science

    researchmap

  • Maternal isobutyl-paraben induce obesity in female rats

    Maiko Kawaguchi, Kaori Morohoshi, Gen Watanabe, Yasuyuki Horii, Kazuyoshi Taya, Masatoshi Morita, Hideki Imai, Nobumasa Kato, Toshiyuki Himi

    JOURNAL OF PHYSIOLOGICAL SCIENCES   60   S195 - S195   2010

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    Web of Science

    researchmap

  • Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor beta 1 and synapsin I in rats cerebral cortex

    Maiko Kawaguchi, Kaori Morohoshi, Erina Saita, Rie Yanagisawa, Gen Watanabe, Hirohisa Takano, Masatoshi Morita, Hideki Imai, Kazuyoshi Taya, Toshiyuki Himi

    JOURNAL OF PHARMACOLOGICAL SCIENCES   109   192P - 192P   2009

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    Web of Science

    researchmap

  • Developmental exposure to pentachlorophenol affects thyroid hormone responsive gene in the brain but not stress response

    Maiko Kawaguchi, Kaori Morohoshi, Rie Yanagisawa, Erina Saita, Gen Watanabe, Masatoshi Morita, Kazuyoshi Taya, Hirohisa Takano, Toshiyuki Himi, Hideki Imai

    NEUROSCIENCE RESEARCH   55   S166 - S166   2006

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    Web of Science

    researchmap

  • Effects of bisphenol a on the progesterone receptor system in the adult female rat brain.

    T Funabashi, A Sano, D Mitsushima, M Kawaguchi, F Kimura

    JOURNAL OF PHARMACOLOGICAL SCIENCES   91   34P - 34P   2003

     More details

    Language:English   Publishing type:Research paper, summary (international conference)  

    Web of Science

    researchmap

  • 脳の記憶学習を,制御するニューロステロイド,変動させる環境ホルモン 内分泌攪乱物質の中枢神経系に及ぼす作用

    舩橋 利也, 美津島 大, 佐野 由加根, 中村 孝博, 川口 真以子, 貴邑 冨久子

    生化学   74 ( 8 )   636 - 636   2002.8

     More details

    Language:Japanese   Publisher:(公社)日本生化学会  

    researchmap

  • 内分泌撹乱物質の中枢作用に関する研究の現在・未来 内分泌攪乱物質が脳に及ぼすエストロジェニック作用とノン・エストロジェニック作用

    舩橋 利也, 川口 真以子, 中村 孝博, 貴邑 冨久子

    日本内分泌学会雑誌   78 ( 1 )   19 - 19   2002.4

     More details

    Language:Japanese   Publisher:(一社)日本内分泌学会  

    researchmap

  • 胎生期および授乳期にBisphenol Aを曝露されたラットの血清甲状腺ホルモン濃度

    川口 真以子, 森田 昌敏, 今井 秀樹, 舩橋 利也, 美津島 大, 貴邑 冨久子

    環境ホルモン学会研究発表会要旨集   4回   359 - 359   2001.12

     More details

    Language:Japanese   Publisher:環境ホルモン学会(日本内分泌撹乱化学物質学会)  

    researchmap

  • 卵巣摘除成熟ラットの視床下部プロジェステロン受容体発現に及ぼすビスフェノールAの影響

    舩橋 利也, 川口 真以子, 貴邑 冨久子

    神経化学   40 ( 2-3 )   466 - 466   2001.9

     More details

    Language:Japanese   Publisher:日本神経化学会  

    researchmap

  • 視床下部プロジェステロン受容体(PR)mRNA発現に及ぼす内分泌攪乱物質の影響

    舩橋 利也, 川口 真以子, 佐野 亜加根, 貴邑 冨久子

    日本内分泌学会雑誌   77 ( 2 )   312 - 312   2001.9

     More details

    Language:Japanese   Publisher:(一社)日本内分泌学会  

    researchmap

  • 内分泌攪乱物質のパルス状黄体形成ホルモン(LH)分泌に及ぼす影響

    舩橋 利也, 川口 真以子, 貴邑 冨久子

    日本生気象学会雑誌   36 ( 3 )   S39 - S39   1999.10

     More details

    Language:Japanese   Publisher:日本生気象学会  

    CiNii Research

    researchmap

  • 卵巣摘除ラットのパルス状LH分泌に対する内分泌攪乱物質の影響

    川口 真以子, 舩橋 利也, 饗庭 祥子, 貴邑 冨久子

    日本内分泌学会雑誌   75 ( 1 )   155 - 155   1999.4

     More details

    Language:Japanese   Publisher:(一社)日本内分泌学会  

    researchmap

▼display all

Presentations

  • Effects of neonatal exposure to 3-Methyl-4-Nitrophenol on partner preference in female rats

    Yukihiro Maeda, Gen Watanabe, Yasuhiko Kondo, Rie Yanagisawa, Maiko Kawaguchi

    The 19th International Congress of Comparative Endocrinology  2025.7  国際比較内分泌学会

     More details

    Event date: 2025.7

    Language:English   Presentation type:Poster presentation  

    Venue:仙台  

    researchmap

  • Effects of lignin sulfonic acid on anxiety-like behavior, organ weights, and plasma hormone levels in male rats

    Keiichi Kozasa, Gen Watanabe, Maiko Kawaguchi

    The 19th International Congress of Comparative Endocrinology  2025.7  国際比較内分泌学会

     More details

    Event date: 2025.7

    Language:English   Presentation type:Poster presentation  

    Venue:仙台  

    researchmap

  • 3-methyl-4-nitro-phenol の新生仔期曝露が雌ラットの性選好性・生殖能力に与える影響

    中村優大, 岩田汐央, 前田侑輝拓, 林実里, 金丸颯, 武藤里加子, 堤恋結, 渡辺元, 近藤保彦, 柳澤利枝, 川口真以子

    日本内分泌撹乱物質学会第26回研究発表会  2024.12  日本内分泌撹乱物質学会

     More details

    Event date: 2024.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • Differences in fecal bacterial composition between inbred Hatano strains of rats with high/low emotional reactivity

    Shuichi Chiba, Tsutomu Shimada, Ryo Ohta, Taichi Hatakeyama, Rie Yanagisawa, Daiya Suzuki, Maiko Kawaguchi

    日本動物心理学会第84回大会  2024.10  日本動物心理学会

     More details

    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • Intrahippocampal Neuromedin U (NmU) is involved in learning and memory, not in anxiety like behavior in the male rat.

    Kaito Sato, Shuichi Chiba, Gen Watanabe, Maiko Kawaguchi

    日本動物心理学会第84回大会  2024.10  日本動物心理学会

     More details

    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • Sustained effect of fenders for suppressing regurgitation behavior and changes of fecal cortisol in captive bottlenose dolphins

    Shio Iwata, Chika Shirakata, Shuto Haneda, Shohei Nagano, Gen Watanabe, Maiko Kawaguch

    日本動物心理学会第84回大会  2024.10  日本動物心理学会

     More details

    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • C3 欠損雌マウス の育児行動およびストレス応答に関する解析

    山下泰, 佐藤海斗, 川口真以子, 佐藤伴, 河野菜摘子

    日本動物学会 第95回長崎大会  2024.9  日本動物学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長崎  

    researchmap

  • 飼育下バンドウイルカにおけるボートフェンダーへの接触行動とその吐き戻し行動抑制効果~Environmental enrichment deviceの影響~

    岩田汐央・白形知佳・羽田秀人・長野翔平・渡辺元・川口真以子

    日本哺乳類学会2024年度大会  2024.9  日本哺乳類学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

    researchmap

  • 健常成熟ラットにおけるDHA及びコリンの分子種別給餌が記憶・学習に与える効果

    大久保剛, 草彅星太郎, 渡辺元, 川口真以子

    第78回日本栄養・食糧学会大会  2024.5  日本栄養・食糧学会大会

     More details

    Event date: 2024.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡  

    researchmap

  • リグニンが雄ラットの性成熟・不安様行動・臓器重量に与える影響

    渡辺元, 小笹圭一, 川口真以子

    超異分野学会2024東京・関東大会  2024.3  超異分野学会

     More details

    Event date: 2024.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • Exposure to tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) at periods of juvenile and adult suppresses sexual behavior, but not neonatal and adult in male rats International conference

    Iwata S, Fumiya K, Kaito S, Hatakeyama T, Watanabe G, Ohta R, Yanagisawa R, Koike E, Suzuki N, Kawaguchi M

    Neuroscience 2023  2023.11  Society for Neuroscience

     More details

    Event date: 2023.11

    Language:English   Presentation type:Poster presentation  

    Venue:Washington (USA)  

    researchmap

  • Does pituitary adenylate cyclase-activating polypeptide (PACAP) cause anxiolytic properties in the rat hippocampus? International conference

    Sato K, Iwata S, Hatakeyama T, Watanabe G, Kawaguchi M

    Neuroscience 2023  2023.11  Society for Neuroscience

     More details

    Event date: 2023.11

    Language:English   Presentation type:Poster presentation  

    Venue:Washington (USA)  

    researchmap

  • Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) antagonist Cause Anxiolytic effects in the Hippocampus of Sprague-Dawley Rat

    Sato K, Iwata S, Hatakeyama T, Watanabe G, Kawaguchi M

    日本動物心理学会第83回大会  2023.10  日本動物心理学会

     More details

    Event date: 2023.10

    Language:English   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • 飼育下バンドウイルカの吐き戻し行動減退策の検討

    岩田汐央, 入田祐実, 大川蓮華, 小林翔平, 井上聰, 細野透, 勝俣悦子, 田谷一善, 川口真以子

    動物の行動と管理学会2023年度大会  2023.9  動物の行動と管理学会

     More details

    Event date: 2023.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:北海道  

    researchmap

  • Effects of Chronic L-α-glycerylphosphorylcholine (α-GPC) Ingestion on Spatial Memory in Adult Male Rats International conference

    Ishii A, Hatakeyama T, Moriya S, Kawaguchi M, Ohkubo T

    The 22nd International Congress of Nutrition  2022.12  IUNS-ICN第22回国際栄養会議

     More details

    Event date: 2022.12

    Language:English   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • 雄ラットのジアゼパム誘導性再認記憶障害における精巣の関与についての検討

    畑 実野里, 石井 敦大, 川口 真以子, 畠山 太一

    JPW2022(第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会)  2022.12  JPW2022(第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会)

     More details

    Event date: 2022.11 - 2022.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜  

    researchmap

  • Effects of Chronic L-α-glycerylphosphorylcholine (α-GPC) Ingestion on Spatial Memory and the hippocampal formation in Adult Male Rats International conference

    Ishii A, Hatakeyama T, Moriya S, Kawaguchi M, Ohkubo T.

    Neuroscience2022  2022.11  Society for Neuroscience

     More details

    Event date: 2022.11

    Language:English   Presentation type:Poster presentation  

    Venue:SanDiego  

    researchmap

  • Identifying anxiety-related genes in the hippocampus of Hatano rats. International conference

    Sato K, Ishii A, Hatakeyama T, Chiba S, Moriya S, Ohta R, Kawaguchi M

    Neuroscience2022  2022.11  Society for Neuroscience

     More details

    Event date: 2022.11

    Language:English   Presentation type:Poster presentation  

    Venue:SanDiego  

    researchmap

  • Administration of progesterone, but not 17-beta-estradiol, tends to improve diazepam-induced place recognition memory deficit in female rats International conference

    Hatakeyama T, Hayashi A, Tokura K, Ishii A, Kobayashi S, Watanabe G, Kawaguchi M

    Neuroscience2022  2022.11  Society for Neuroscience

     More details

    Event date: 2022.11

    Language:English   Presentation type:Poster presentation  

    Venue:SanDiego  

    researchmap

  • Hatanoラットの海馬を用いた不安症関連遺伝子の探求

    佐藤海斗, 石井敦大, 畠山太一, 千葉秀一, 守屋彰悟, 太田亮, 川口真以子

    オンライン開催  2022.9 

     More details

    Event date: 2022.9

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • アセナフテンの曝露量の変動が雄ラットに及ぼす毒性影響

    加藤史也,池田菜央,秋元貴尋,岩田汐央, 田中杏苗,佐藤海斗,石井敦大,畠山太一,渡 辺元,太田亮,柳澤利枝,小池英子,鈴木規 之,川口真以子

    環境化学物質 3 学会合同大会  2022.6  日本環境化学会、環境ホルモン学会、日本環境毒性学会

     More details

    Event date: 2022.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:富山県 富山国際会議場   Country/Region:Japan  

    researchmap

  • 慢性的なα - グリセリルホスホリルコリン (α -GPC)摂取が 健康な成熟ラットの空間 記憶に与える影響

    石井 敦大, 畠山 太一, 川口 真以子, 大久保 剛

    第76回日本栄養・食糧学会大会  2022.6  日本栄養・食糧学会

     More details

    Event date: 2022.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:兵庫県神戸市 武庫川女子大学   Country/Region:Japan  

    researchmap

  • アゼパム投与がラットの自発的物体再認テストに与える影響に対する性差の検討

    畠山太一,小淵鼓, 林綾音,石井敦大, 川口真以子

    第40回日本生理心理学会大会  2022.5  日本生理心理学会

     More details

    Event date: 2022.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:兵庫県西宮市 関西学院大学上ケ原キャンパス   Country/Region:Japan  

    researchmap

  • ジアゼパム投与による雌ラットの再認記憶障害とプロゲステロンとの関連

    畠山太一,林綾音,石井敦大,小林翔平,渡辺元,川口真以子

    第34回 日本行動神経内分泌研究会  2021.9  日本行動神経内分泌研究会

     More details

    Event date: 2021.9

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Tris(1,3-dichloro-2-propyl)phosphates (TDCIPP)がストレス応答系に及ぼす毒性影響

    秋元貴尋・畠山太一・鈴木規之・川口真以子

    環境ホルモン学会第23回研究発表会  2021.9  環境ホルモン学会

     More details

    Event date: 2021.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web開催  

    researchmap

  • ベンゾジアゼピン系抗不安薬であるジアゼパムが卵巣摘出ラットの自発的再認記憶に与える影響.

    畠山太一・権純熊・林綾音・川口真以子

    第39回日本生理心理学会  2021.5  日本生理心理学会

     More details

    Event date: 2021.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web開催  

    researchmap

  • リン酸トリス(2-ブトキシエチル)によるアレルギー性喘息の増悪と腸内細菌叢の変化

    柳澤利枝,小池英子,Tin-Tin Win-Shwe,川口真以子,嶋田努,高野裕久

    第91回日本衛生学会学術総会  2021.3  日本衛生学会

     More details

    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web開催  

    researchmap

  • 災害・事故等に起因する化学物質の非定常的曝露による健康影響評価の必要性

    柳澤利枝,川口真以子,小池英子,鈴木規之.

    第91回日本衛生学会学術総会  2021.3  日本衛生学会

     More details

    Event date: 2021.3

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:Web開催  

    researchmap

  • リン酸トリス(1,3-ジクロロ-2-プロピル)の混餌経口曝露がアレルギー性喘息マウスモデルの肺炎症に及ぼす影響

    柳澤利枝, 小池英子, Tin-Tin Win-Shwe, 川口真以子, 嶋田努, 高野裕久

    第27回日本免疫毒性学会学術年会  2020.9  日本免疫毒性学会

     More details

    Language:Japanese  

    Venue:Web開催  

    researchmap

  • Tris(1,3-dichloro-2-propyl)phosphate(TDCIPP)の幼若期曝露は成熟期曝露後の毒性影響に変化を及ぼすか

    秋元貴尋, 小林翔平, 磯部翔一, 畠山太一, 太田亮, 柳澤利枝, 小池英子, 鈴木規之, 川口真以子

    第64回日本薬学会関東支部大会  2020.9  日本薬学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web開催  

    researchmap

  • Tris(1,3-dichloro-2-propyl)phosphate(TDCIPP)の幼若期、成熟期2回曝露が成熟期雄ラットに及ぼす毒性影響

    秋元貴尋, 小林翔平, 磯部翔一, 畠山太一, 太田亮, 柳澤利枝, 小池英子, 鈴木規之, 川口真以子

    第47回日本毒性学会学術年会  2020.6  日本毒性学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web開催  

    researchmap

  • 4Tris (1,3-dichloro-2-propyl) phosphate の 7 日間反復経口投与が成熟期雄ラットに及ぼす毒性影響

    小林翔平・阿部光海・大沼愛美・畠山太一・河野菜摘子・宮戸健二・斉藤義明・柳澤利枝・小池英子・鈴木規之・川口真以子

    第22回環境ホルモン学会研究発表会  2019.12  日本内分泌撹乱化学物質学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京大学弥生講堂(東京都文京区本郷)  

    researchmap

  • 災害・事故と非定常曝露に対するリスク評価手法

    鈴木規之, 小池英子, 柳澤利枝, 川口真以子

    2019年度第32 回日本リスク学会年次大会  2019.11  日本リスク学会

     More details

    Language:Japanese  

    Venue:東京工業大学大岡山キャンパス  

    researchmap

  • アオウミガメ小笠原諸島個体群において日陰がウミガメ幼体の特性に与える影響について

    小林翔平, 遠藤大輔, 近藤理美, 北山知代, 新井克彦, 渡辺元, 川口真以子

    第30回日本ウミガメ会議  2019.11  日本ウミガメ協議会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:和歌山県みなべ町  

    researchmap

  • The effect of environmental enrichment on hippocampal neuroplasticity-related genes in Hatano rats. International conference

    Asano, H., Okawa, H., Nakayama, A., Tokuoka, H., Kasai, W., Ota, R. and Kawaguchi, M

    Society for Neuroscience 2019.  2019.10  Society for Neuroscience

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Chicago, Illinois, USA  

    researchmap

  • Genetic and Endocrinological Analysus of Stress Response and Angsiety-Like Behaviour by Cross-Fostered Hatano Rats International conference

    Akimoto, T., Kawakami, K., Ichikawa, M., Horii, Y., Nakajima, S., Hatakeyama, T., Tokuoka, H., Ota, R., Soga, T., Ishwar S Parhar. and Kawaguchi, M

    Society for Neuroscience 2019.  2019.10  Society for Neuroscience

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Chicago, Illinois, USA  

    researchmap

  • Sutability of sociality research using Hatano rats International conference

    Abe, K., Endo, S., Yanagisawa, R., Ota, R. and Kawaguchi, M

    Society for Neuroscience 2019.  2019.10  Society for Neuroscience

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Chicago, Illinois, USA  

    researchmap

  • Hatano高回避系(HAA)及び低回避系(LAA)ラットは養母交換により不安様行動・ストレス内分泌応答が変化する

    堀井康行・川上光太郎・徳岡秀代・太田亮・田谷一善・川口真以子

    第162回日本獣医学会学術集会  2019.9  日本獣医学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:茨城県つくば市  

    researchmap

  • Hatano ラットの社会性再認記憶の系統差の検討

    畠山太一, 川上光太郎, 大河原利, 武者晃司, 太田亮, 川口真以子

    第42回日本神経科学大会  2019.7  日本神経科学学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:新潟  

    researchmap

  • The Effects of Environmental Enrichment on Anxiety-Like Behavior, Learning Behavior and Hippocampal Gene Expression in Hatano Rats. International conference

    Asano, H., Nakayama, A., Okawa, H., Tokuoka, H., Ota, R., Kasai, W. and Kawaguchi, M

    The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019).  2019.6 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • Effect of Environmental Enrichment on Reproductive Behavior in Hatano Rats. International conference

    Okawa, H., Ota, R., Nakayama, A., Asano, H., Kasai, W., Kobayashi, S. and Kawaguchi, M

    The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019).  2019.6 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • 文脈恐怖条件づけ場面におけるHatanoラットの特徴

    畠山太一・大河原利・太田亮・川口真以子

    第37回日本生理心理学会大会  2019.5  日本生理心理学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:埼玉県越谷  

    researchmap

  • Tris (1,3-dichloro-2-propyl) Phosphate (TDCIPP) の幼若期・成熟期曝露の毒性影響

    中山愛里, 磯部安奈, 阿部光海, 坂井亮太, 白藤勇登, 柳澤利枝, 小池栄子, 鈴木規之, 川口真以子.

    環境ホルモン学会 第12回研究発表会  2018.12  環境ホルモン学会第12回研究発表会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • 幼若期Hatanoラットの社会性の獲得・発達の特徴

    阿部 光海, 服部 達哉, 前田 侑乃, 柳澤 利枝, 太田 亮, 川口 真以子

    第161回日本獣医学会学術集会  2018.9 

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:つくば  

    researchmap

  • Social companions may affect rat pup physical strength and anxiety calls

    Anna Isobe, Maiko Kawaguchi

    The 78th Annual Meeting of the Japanese Society for Animal Psychology  2018.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Hiroshima  

    researchmap

  • The effects of environmental enrichment on anxiety-like behavior and hippocampal gene expression in Hatano rats.

    Hikaru Asano, Airi Nakayama, Hasuka Okawa, Hideyo Tokuoka, Ryo Ota, Maiko Kawaguchi

    The 78th Annual Meeting of the Japanese Society for Animal Psychology  2018.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Hiroshima  

    researchmap

  • Effect of environmental enrichment on reproductive behavior and body weight in Hatano rats

    Airi Nakayama, Hasuka Okawa, Hikaru Asano, Hideyo Tokuoka, Ryo Ohta, Maiko Kawaguchi

    The 78th Annual Meeting of the Japanese Society for Animal Psychology  2018.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Hiroshima  

    researchmap

  • Influence of Cross-Fostering on Anxiety-Like Behavior and Expression of Wnt3a Gene in Hippocampus in Hatano Rats

    Kotaro Kawakami, Shingo Nakazima, Tomoko Soga, Ishwar S Parhar, Ryo Ohta, Maiko Kawaguchi

    The 78th Annual Meeting of the Japanese Society for Animal Psychology  2018.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Hiroshima  

    researchmap

  • Assessing the Effect of Environmental Enrichment on Hatano Rat Sexual Behavior and the Investigation of its Contribution Factor by use of Social Interaction Test. International conference

    Okawa, H., Hattori, T., Nakayama, A., Ota, R. & Kawaguchi, M.

    18th Asian Australasian Animal Production Congress  2018.8 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • The Effect of Environmental Enrichment on Emotional Behavior snd Hippocampus Gene Expression in Hatano Rats . International conference

    Nakayama, A., Asano, H., Okawa, H., Tokuoka, H., Ota, R., Kawaguchi, M.

    18th Asian Australasian Animal Production Congress  2018.8 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Malaysia  

    researchmap

  • The effect of environmental enrichment on hippocampus gene expression and blood corticosterone concentration in Hatano rats. International conference

    Airi Nakayama, Hasuka Okawa, Hikaru Asano, Hideyo Tokuoka, Meihua Zheng, Shaoxia Pu, Gen Watanabe, Ryo Ota, Maiko Kawaguch

    18th World Congress of Basic and Clinical Pharmacology  2018.7 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Kyoto  

    researchmap

  • Littermates can affect on maternal-separation inducide ultrasonic vocalization in rat pups. International conference

    Anna Isobe, Maiko Kawaguch

    18th World Congress of Basic and Clinical Pharmacology  2018.7 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Kyoto  

    researchmap

  • ラットにおける恐怖への応答について

    井上拓人, 大河原 利, 蔵原崇志, 川上光太郎, 太田 亮, 川口真以子

    日本家畜管理学会・応用動物行動学会2018年度春季研究発表  2018.3 

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    researchmap

  • Contextual fear conditioning test in Hatano high and low avoidance rats International conference

    Toru OKAWARA, Ryo OHTA, Takuto INOUE, Misa KUBONOYA, Maiko KAWAGUCHI

    Neuroscience 2017  2017.11 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • Effect of environmental enrichment on emotional, learning behavior, and hippocampus BDNF expression in Hatano rats. International conference

    Airi Nakayama, Hasuka Okawa, Hikaru Asano, Hideyo Tokuoka, Ryo Ota, Maiko Kawaguchi

    Neuroscience 2017  2017.11 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • Hatano rats suitable as metabolic syndrome model focusing on feeding behavior and physiological strain differences. International conference

    Anna Isobe, Gaku Shimazaki, Tomoyoshi Sakawa, Tsutomu Shimada, Masaki Aburada, Takahiro Nakamura, Ryo Ota, Maiko Kawaguchi

    Neuroscience 2017  2017.11 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • Strain differences of learning ability and emotional behavior in Hatano high and low avoidance rats International conference

    Kotaro Kawakami, Toru Okawara, Koji Musya, Ryo Ohta, Yasuyuki Hori, Maiko Kawaguchi

    Neuroscience 2017  2017.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Washington DC  

    researchmap

  • Hatano ラットの Y 字型迷路を用いた空間記憶における特徴

    川上光太郎, 大河原利, 蔵原崇志, 井上拓人, 太田亮, 川口真以子

    行動2017(日本動物心理学会、日本動物行動学会、応用動物行動学会、日本家畜管理学会、日本行動神経内分泌研究会合同大会)  2017.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • Hatano ラットの恐怖条件付け文脈学習試験における行動とその関連脳領域の特徴

    大河原利, 井上拓人, 太田亮, 川口真以子

    行動2017(日本動物心理学会、日本動物行動学会、応用動物行動学会、日本家畜管理学会、日本行動神経内分泌研究会合同大会)  2017.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • 同腹仔の存在が母子分離による仔ラットの超音波発声に及ぼす影響

    磯部安菜, 川口真以子

    行動2017(日本動物心理学会、日本動物行動学会、応用動物行動学会、日本家畜管理学会、日本行動神経内分泌研究会合同大会)  2017.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 環境エンリッチメントが Hatano ラットの情動・性行動、血中テストステロン濃度 および海馬 BDNF 遺伝子発現に及ぼす影響

    中山愛里, 大川蓮華, 浅野洸, 鄭梅花, 普少瑕, 渡辺元, 徳岡秀代, 太田亮, 川口 真以子

    行動2017(日本動物心理学会、日本動物行動学会、応用動物行動学会、日本家畜管理学会、日本行動神経内分泌研究会合同大会)  2017.8 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Effect of enviromental enrichment on emotional, reproductive behavior and hippocampus BDNF expression in Hatano rats.

    中山愛里, 大川蓮華, 浅野洸, 徳岡秀代, 太田亮, 川口 真以子

    第40回日本神経科学大会  2017.7 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:幕張  

    researchmap

  • Contextual fear conditioning tests in Hatano high and low avoidance rats

    大河原利, 太田亮, 井上拓人, 窪谷美紗, 川口真以子

    第40回日本神経科学大会  2017.7 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 環境エンリッチメントがHatanoラットの学習・性行動に与える影響

    大川蓮華, 中山愛里, 太田 亮, 川口真以子

    日本家畜管理学会・応用動物行動学会2017年度春季合同研究発表会  2017.3 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

    researchmap

  • Behavioral characteristics of Hatano high and low avoidance rats that have been respectively bred based on the active avoidance learning test

    2017.3 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 幼若期雌ラットにethynyl estradiolおよびtriphenyl phosphateを28日間経口投与すると、成熟後の性選好性、性行動に影響を及ぼす

    磯部 安菜, 中山 愛里。 服部 達哉, 宍戸 浩孝, 鈴木 剛, 滝上 英孝, 川口 真以子

    第90回日本薬理学会年会  2017.3  日本薬理学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:長崎  

    researchmap

  • Effect of environmental enrichment on emotional and reproductive behavior in Hatano rats

    2017.3 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 幼若期 tris(1,3-dichloroisopropyl)phosphate (TDCIPP) と triphenyl phosphate (TPhP)曝露は雄ラットの性行動へ濃度依存的な抑制効果をもつ

    服部達哉, 神島愛末, 鈴木 剛, 松神秀徳, 渡辺 元, 近藤保彦, 滝上英孝, 川口真以子

    第19回 環境ホルモン学会  2016.12  環境ホルモン学会 (正式名:日本内分泌撹乱化学物質学会)

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:つくば  

    researchmap

  • 環境エンリッチメントがHatanoラットの生殖行動も及ぼす影響

    中山愛里, 大川蓮華, 太田 亮, 川口真以子

    第109回 日本繁殖生物学会  2016.9  日本繁殖生物学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神奈川 相模原市  

    researchmap

  • 恐怖条件付け文脈学習試験においてHatanoラットの高回避系は低回避系に比べ高いフリージングと超音波発声を示す

    大河原 利, 井上 拓人, 太田 亮, 川口真以子

    第39回 日本神経科学大会  2016.7  日本神経科学学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜  

    researchmap

  • ストレス負荷がHatanoラットのスクロース選好性に及ぼす影響

    宍戸浩孝, 川口真以子

    日本畜産学会第121回大会  2016.3  日本畜産学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

    researchmap

  • 仔ラットの母子分離誘発啼鳴反応の発声回数に対する抗不安薬ジアゼパムの抑制作用には性差がある

    磯部安奈, 川口真以子

    第89回日本薬理学会年会  2016.3  日本薬理学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜  

    researchmap

  • 幼若期雌ラットへのethynyl estradiol(EE)とtriphenyl phosphate(TPhP)の28日間曝露が成熟後の臓器重量、情動行動、性選好性、性行動に及ぼす影響

    中山愛里, 服部達哉, 宍戸浩孝, 磯部安菜, 鈴木剛, 滝上英孝, 川口真以子

    環境ホルモン学会第18回研究発表会  2015.12  環境ホルモン学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:栃木  

    researchmap

  • 幼若期雌ラットへのethynyl estradiolとtriphenyl phosphateの28日間曝露が成熟後の性行動に及ぼす影響

    中山愛里, 服部達哉, 大河原利, 田辺郁也, 磯部安菜, 宍戸浩孝, 鈴木剛, 滝上英孝, 川口真以子

    第42回日本神経内分泌学会・第23回日本行動神経内分泌研究会 合同学術集会  2015.9  日本神経内分泌学会・日本行動神経内分泌研究会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台  

    researchmap

  • Altered emotional reactivity of offspring induced by cross-fostering between Hatano high and low active avoidance rats, and its relationship with maternal care

    2015.7 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 養母交換が雄HATANOラットの受動回避学習へ及ぼす影響

    大河原 利, 佐藤 洸輔, 中嶋 慎吾, 太田 亮, 堀井 康行, 川口 真以子

    第62回日本実験動物学会総会  2015.5  日本実験動物学会総会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • 生後24時間以内の雌ラットへのethynyl estradiol 曝露が受動回避学習に及ぼす影響

    田邉郁也, 小峰千亜希, 吉田緑, 川口真以子

    第62回日本実験動物学会総会  2015.5  日本実験動物学会総会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • 雌ラットへの生後24時間以内ethynyl estradiol 曝露が大脳皮質と海馬のestrogen receptor(ER)α及びERβ発現に及ぼす影響

    立川直之, 志賀健臣, 中村孝博, 小峰千亜希, 堀井康之, 渡辺元, 田谷一善, 溝口康, 吉田緑, 川口真以子

    第62回日本実験動物学会総会  2015.5  日本実験動物学会総会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都  

    researchmap

  • Effects of Neonatal Ethynyl Estradiol Exposure to Female Rats on Partner Preference, Territorial and Sexual Behavior

    2014.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Effect of anti-androgen and tris(1,3- dichloro-2-propyl)phosphate (TDCIPP) on sexual behavior, sexual preference, organ weight and plasma concentration of testosterone of male rats

    2014.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Cross-fostering between Hatano high and low active avoidance rats altered emotional reactivity of male offspring International conference

    Yasuyuki HORII, Ryo OHTA, Kosuke TAKAHASHI, Yuji SATO, Kosuke SATO, Shingo NAKAJIMA, Yuki SHIRAISHI, Maiko KAWAGUCHI

    Neuroscience 2014  2014.11  Society for Neuroscience

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Washington DC U.S.A  

    researchmap

  • Effects of Neonatal Ethynyl Estradiol Exposure to Female Rats on Partner Preference, Territorial and Sexual Behavior International conference

    Tatsuomi Shiga, Takahiro J. Nakamura, Yasushi Mizoguchi, Chiaki Komine, Yoshikuni Goto, Manami Kamishima, Midori Yoshida, Yasuhiko Kondo, Maiko Kawaguchi

    Neuroscience 2014  2014.11  Society for Neuroscience

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Washington DC、U.S.A  

    researchmap

  • Neonatal exposure to ethinyl estradiol decreased the learning performance and the expression levels of ERα in adult female rats International conference

    Tatsuomi Shiga, Takahiro J. Nakamura, Yasushi Mizoguchi, Chiaki Komine, Yoshikuni Goto, Manami Kamishima, Midori Yoshida, Yasuhiko Kondo, Maiko Kawaguchi

    Neuroscience 2014  2014.11  Society for Neuroscience

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Washington DC、U.S.A  

    researchmap

  • Neonatal exposure to ethinyl estradiol decreased the the expression levels of ERα in adult female rats International conference

    Shiga T, Nakamura T J, Mizoguchi Y, Kondo Y, Kawaguchi M

    5th International NeuroMalaysia Symposium  2014.9  NeuroMalaysia Society

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Malaysia  

    researchmap

  • Relationship between elevated plus maze arm structure and anxiety-like behavior in rats: the presence or absence of open arm ledges vs opaqueness of closed arm stucture walls

    2014.9 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 生後24時間以内のethynyl estradiol曝露が雌ラットの縄張り行動と社会性行動へ及ぼす影響

    小峰千亜希, 近藤保彦, 吉田緑, 川口真以子

    第20回日本行動神経内分泌研究会  2014.9  日本行動神経内分泌研究会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:秩父  

    researchmap

  • 高架十字試験の構造変化に伴うラットの不安様行動の変化

    高橋光佑, 堀井康行, 佐藤祐司, (川口真以子)

    日本畜産学会第118回大会  2014.3  日本畜産学会第

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:つくば  

    researchmap

  • 幼若期及び成熟期のTDCIPP及びflutamide慢性曝露が雄ラットの性行動、副生殖腺重量、血中ホルモン濃度に及ぼす影響

    植村英恵, 神島愛未, 堀井康行, 渡辺元, 田谷一喜, 滝上英孝, 鈴木剛, 近藤保彦, 川口 真以子

    日本畜産学会第118回大会  2014.3  日本畜産学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:つくば  

    researchmap

  • 生後24時間以内の雌ラットへのethynyl estradiol曝露が学習行動に及ぼす影響

    千本隆志, 神島愛未, 小峰千亜希, 吉田緑, 川口真以子

    日本畜産学会第118回大会  2014.3  日本畜産学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:つくば  

    researchmap

  • Exposure to ethinyl estradiol within 24 hours of birth decreases the expression levels of ERα in adult female rats

    2013.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Neonatal exposure to ethinyl estradiol influences the expression levels of estrogen receptor α in the adult brain of female rats International conference

    Shiga, T.(Nakamura, T. J., Goto, Y., Mizoguchi, Y., Komine, C., Kamishima, M., Yoshida, M., Kondo, Y., Kawaguchi, M.)

    Neuroscience 2013  2013.11  Society for Neuroscience

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:San Diego、U.S.A  

    researchmap

  • EFFECTS OF ESTROGENIC COMPOUNDS EXPOSURE WITHIN 24 h AFTER BIRTH ON PARTNER PREFERENCE AND SEXUAL BEHAVIOR IN FEMALE RATS International conference

    Komine, C., Kamishima, M., Yoshida, M., Kondo, Y., Kawagushi, M.(Kawaguchi, M.)

    Neuroscience 2013  2013.11  Society for Neuroscience

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:San Diego、U.S.A  

    researchmap

  • Effects of estrogenic compounds exposure within 24 h after birth on feeding, learning and sexual behavior in female rats International conference

    Komine, C., Kamishima, M., Senbon, T., Uemura, H., Yoshida, M., Kondo, Y., Kawaguchi, M.

    4th International NeuroMalaysia Symposium  2013.9  NeuroMalaysia Society

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Malaysia  

    researchmap

  • EFFECTS OF NEONATAL SINGLE INJECTION OF ETHINYL ESTRADIOL ON FEEDING, LEARNING AND SEXUAL BEHAVIORS IN ADULT FEMALE RATS

    Kamishima, M., Kobayashi, Y., Senbon, T., Komine, C., Uemura, H., Yoshida, M., Kondo, Y., Kawaguchi, M.

    The 17th FAVA Congress  2013.1  Federation of Asian Veterinary Associations

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Taipei, Taiwan  

    researchmap

  • Effect of perinatal ethynyl estradiol exposure on female exploratory behavior

    Asakawa H., Senbon T., Kamishima M., Kobayashi Y., Yoshida M., Kawaguchi M.

    The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research  2012.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Estrogen receptor α expression levels vary in adult female rats exposed to Ethynyl estradiol within 24 hours of birth

    Shiga T., Mizoguchi Y., Kawaguchi M.

    The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research  2012.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Effect of perinatal ethynyl estradiol exposure on female rats' partner preference

    Odajima Y., Miyata A., Nakajima H., Yoshida M., Kawaguchi M.

    The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research  2012.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • Male Hatano High-avoidance Rats Show High Aversive Learning and High Anxiety-like Behaviors as Compared to Male Low-avoidance Rats

    Yasuyuki Horii, Ryo Ohta, Akihiro Hirano, Gen Watanabe, Toshiyuki Himi, Kazuyoshi Taya, Maiko Kawaguchi

    The 35th Annual Meeting of the Japan Neuroscience Society  2012.9 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • 出生直後の雌ラットethynyl estradiol曝露が成熟後の性行動に及ぼす影響

    小峰千亜希,近藤保彦,植村英恵,千本隆志,川口真以子

    日本繁殖生物学会第105回大会  2012.9  日本繁殖生物学会

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:つくば  

    researchmap

  • 出生直後のEthynyl Estradiol曝露がラットの学習行動に及ぼす影響

    千本隆志,小林由紀,近藤保彦,川口真以子

    第17回日本行動神経内分泌研究会  2012.8 

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    researchmap

  • 雄性Hatano高回避系および低回避系ラットの不安・学習能力と養母交換が及ぼす影響

    堀井康行, 小澤愛, 丹羽鈴夏, 橋倉千聖, 平野顕宏, 太田亮, 渡辺元, 田谷一善, 氷見敏行, 川口真以子

    第38回日本神経内分泌学会  2011.11  日本神経内分泌学会

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

    researchmap

  • The characteristics of Hatano high- and low-avoidance rats as a model for developmental disorder

    Yasuyuki Horii, Itsumi Ozawa, Ryo Ohta, Gen Watanabe, Kazuyoshi Taya, Toshiyuki Himi, and Maiko Kawaguchi

    8th International Congress of Comparative Physiology and Biochemistry  2011.6 

     More details

    Language:English   Presentation type:Poster presentation  

    researchmap

  • Behavioral profile in ovariectomized female Hatano high- and low-avoidance rats

    The 14th International Congress of Endocrinology  2010.3 

     More details

    Language:English   Presentation type:Oral presentation (general)  

    researchmap

  • Maternal isobutyl-paraben exposure alters anxiety, learning performance, and social recognition in adult rats

    The 36th Japan Neuroendocrine Society  2009.9 

     More details

    Language:English   Presentation type:Oral presentation (general)  

    researchmap

  • Developmental exposure to Pentachlorophenol affects thyroid hormone responsive gene in the brain but not stress response

    The 29th Annual Meeting of the Japan Neuroscience Society  2006.7 

     More details

    Language:English   Presentation type:Oral presentation (general)  

    researchmap

  • Reductions of food intake arising from voluntary running wheel exercise are attenuated by central injection of a CRF antagonist

    Neuroscience 33rd Annual Meeting  2003.10 

     More details

    Language:English   Presentation type:Oral presentation (general)  

    researchmap

  • Effects of environmental estrogens on pulsatile luteinizing hormone secretion in adult female rats

    The 4th International Congress of neuroendocrinology  1998.10 

     More details

    Language:English   Presentation type:Oral presentation (general)  

    researchmap

▼display all

Research Projects

  • Fundamental understanding for establishing a novel method of temperature control using an animal model of CNS-regulated hypothermia.

    Grant number:22H00396  2022.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

      More details

    Grant amount:\42120000 ( Direct Cost: \32400000 、 Indirect Cost:\9720000 )

    researchmap

  • 室内ダスト中の化学物質曝露に よる腸内細菌叢の変化は生体高 次機能をかく乱し得るか

    2017.4 - 2020.3

    基盤研究B(一般) 

    国立研究開発法人国立環境研究所 柳澤 利枝

      More details

    Authorship:Coinvestigator(s) 

    Grant amount:\9000000 ( Direct Cost: \9000000 )

    researchmap

  • 製品に含まれる化成品及び不純物に由来する有害廃棄物対策と循環方策構築に向けた研究

    2013.4 - 2015.3

    独立行政法人環境 再生保全機構 

    国立研究開発法人国立環境研究所 滝上英孝

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\10267000 ( Direct Cost: \10267000 )

    researchmap

  • Identification of in vitro reproductive toxicants in house and office environments

    Grant number:23681011  2011.11 - 2014.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (A)

    SUZUKI Go, KAWAGUCHI Maiko

      More details

    Grant amount:\15470000 ( Direct Cost: \11900000 、 Indirect Cost:\3570000 )

    Indoor dust is a sink for many kinds of pollutants, including flame retardants (FRs). To reveal high-priority endpoints of and contaminant candidates in indoor dust, using reporter gene assays based on human U2OS cell lines, we characterized the endocrine-disrupting potencies of crude extracts of indoor dust collected from Japan and abroad and for 23 selected FRs. Indoor dust extracts were agonistic to ERa, GR, and PPARg2 and antagonistic against AR, PR, GR, and PPARg2. A majority of FRs was agonistic to ERa and PPARg2 only, and some FRs demonstrated antagonism against all tested nuclear receptors. Hierarchical clustering clearly indicated agonism of ERa and antagonism of AR and PR were common. Given our previous results regarding the concentrations of FRs in indoor dust and in light of our current results, candidate contributors to these effects includes FRs such TDCIPP. We have just started in vivo reproductive toxicity testing for TDCIPP by testing method established in this study.

    researchmap

  • 内分泌かく乱化学物質が甲状腺機能とストレス応答に及ぼす影響の検証

    2003.4 - 2006.3

    特別研究員奨励費 

    川口真以子

      More details

    Authorship:Principal investigator 

    researchmap