University of Cambridge Department of Materials Science and Metallurgy Visiting Scholar

2001.10 - 2002.9

Research Assistant

1993.4 - 2003.2

Researcher

1992.4 - 1993.3

日本セラミックス協会   「セラミックス」誌編集委員  

2020.5 - 2023.4   

無機マテリアル学会   「無機マテリアル」誌編集委員長  

2019.4 - 2021.3   

日本無機リン化学会   「Phosphorus Res. Bull.」誌編集委員長  

2018.9   

無機マテリアル学会   常任理事  

2018.6   

無機マテリアル学会   理事  

2016.6 - 2018.5   

日本バイオマテリアル学会   評議員  

2012.4   

日本無機リン化学会   「Phosphorus Res. Bull.」誌編集委員  

2010.10   

日本無機リン化学会   広報担当理事・「PHOSPHORUS LETTER」誌編集委員長  

2010.10 - 2018.9   

日本無機リン化学会   理事  

2010.9   

無機マテリアル学会   「無機マテリアル」誌編集委員  

2010.4   

日本バイオマテリアル学会   「バイオマテリアル」誌編集委員  

2010.4   

日本セラミックス協会   生体関連材料部会 副部会長  

2007.10 - 2013.9   

日本セラミックス協会   「セラミックス」誌編集委員  

2004.5 - 2006.4   

日本セラミックス協会   生体関連材料部会 評議員  

2003.10   

日本無機リン化学会   評議員  

2003.10   

無機マテリアル学会   評議員  

2003.4   

無機マテリアル学会   企画行事委員  

2002   

Proteomics of serum proteins adsorbed onto hydroxyapatite single-crystal particles with an anisotropic structure

Erika Onuma, Hayato Ito, Maki Sasaki, Nobuyuki Kanzawa, Keiji Kito, Mamoru Aizawa

Materialia   32   101926 - 101926   2023.12

Identification of Proteins Adsorbed on Hydroxyapatite Ceramics with a Preferred Orientation to a-Plane

Erika Onuma, Takayuki Honda, Hideyuki Yoshimura, Tappei Nishihara, Atsushi Ogura, Nobuyuki Kanzawa, Mamoru Aizawa

Crystals   13 ( 9 )   1318 - 1318   2023.8

Preparation of antimicrobial calcium phosphate/protamine composite powders with fluoride ions using octacalcium phosphate. International journal

Daisuke Koizumi, Kitaru Suzuki, Rie Togawa, Kosuke Yasui, Keishi Iohara, Michiyo Honda, Mamoru Aizawa

Journal of materials science. Materials in medicine   33 ( 4 )   35 - 35   2022.4

Preparation of protamine-adsorbed calcium phosphate powders and their antibacterial property

Daisuke Koizumi, Kitaru Suzuki, Hirogo Minamisawa, Rie Togawa, Kosuke Yasui, Keishi Iohara, Michiyo Honda, Mamoru Aizawa

Journal of Asian Ceramic Societies   10 ( 1 )   230 - 240   2022.1

Living reactions of tissue-engineered bone derived from apatite-fiber scaffold in rat subcutaneous tissues

Kitaru Suzuki, Michiyo Honda, Tomokazu Matsuura, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   130 ( 1 )   65 - 73   2022.1

Influence of Culture Period on Osteoblast Differentiation of Tissue-Engineered Bone Constructed by Apatite-Fiber Scaffolds Using Radial-Flow Bioreactor. International journal

Kitaru Suzuki, Jun Fukasawa, Maiko Miura, Poon Nian Lim, Michiyo Honda, Tomokazu Matsuura, Mamoru Aizawa

International journal of molecular sciences   22 ( 23 )   2021.12

Influence of Culture Period on Osteoblast Differentiation of Tissue-Engineered Bone Constructed by Apatite-Fiber Scaffolds Using Radial-Flow Bioreactor

Kitaru Suzuki, Jun Fukasawa, Maiko Miura, Poon Nian Lim, Michiyo Honda, Tomokazu Matsuura, Mamoru Aizawa

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   22 ( 23 )   2021.12

Regulating size of silver nanoparticles on calcium carbonate via ultrasonic spray for effective antibacterial efficacy and sustained release. International journal

Mayu Ueda, Tomohiro Yokota, Michiyo Honda, Poon Nian Lim, Naoya Osaka, Masashi Makita, Yasutoshi Nishikawa, Toshihiro Kasuga, Mamoru Aizawa

Materials science & engineering. C, Materials for biological applications   125   112083 - 112083   2021.6

Regulating size of silver nanoparticles on calcium carbonate via ultrasonic spray for effective antibacterial efficacy and sustained release

Mayu Ueda, Tomohiro Yokota, Michiyo Honda, Poon Nian Lim, Naoya Osaka, Masashi Makita, Yasutoshi Nishikawa, Toshihiro Kasuga, Mamoru Aizawa

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS   125   2021.6

Zoledronic Acid-Loaded β-TCP Inhibits Tumor Proliferation and Osteoclast Activation: Development of a Functional Bone Substitute for an Efficient Osteosarcoma Treatment. International journal

Yuka Kameda, Mamoru Aizawa, Taira Sato, Michiyo Honda

International journal of molecular sciences   22 ( 4 )   2021.2

An antibacterial coated polymer prevents biofilm formation and implant-associated infection. International journal

Hiroko Ishihama, Ken Ishii, Shigenori Nagai, Hiroaki Kakinuma, Aya Sasaki, Kenji Yoshioka, Tetsuya Kuramoto, Yuta Shiono, Haruki Funao, Norihiro Isogai, Takashi Tsuji, Yasunori Okada, Shigeo Koyasu, Yoshiaki Toyama, Masaya Nakamura, Mamoru Aizawa, Morio Matsumoto

Scientific reports   11 ( 1 )   3602 - 3602   2021.2

Bioresorbable porous β-tricalcium phosphate chelate-setting cements with poly(lactic-co-glycolic acid) particles as pore-forming agent: fabrication, material properties, cytotoxicity, and in vivo evaluation

Akihiro Ando, Maho Kamikura, Yuko Takeoka, Masahiro Rikukawa, Kazuaki Nakano, Masaki Nagaya, Hiroshi Nagashima, Mamoru Aizawa

Science and Technology of Advanced Materials   22 ( 1 )   511 - 521   2021

Potential Application of Protamine for Antimicrobial Biomaterials in Bone Tissue Engineering. Reviewed International journal

Michiyo Honda, Morio Matsumoto, Mamoru Aizawa

International journal of molecular sciences   21 ( 12 )   2020.6

Bactericidal and Bioresorbable Calcium Phosphate Cements Fabricated by Silver-Containing Tricalcium Phosphate Microspheres Reviewed

Michiyo Honda, Yusuke Kawanobe, Kohei Nagata, Ken Ishii, Morio Matsumoto, Mamoru Aizawa

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   21 ( 11 )   2020.6

Potential Application of Protamine for Antimicrobial Biomaterials in Bone Tissue Engineering Reviewed

Michiyo Honda, Morio Matsumoto, Mamoru Aizawa

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   21 ( 12 )   2020.6

Bactericidal and Bioresorbable Calcium Phosphate Cements Fabricated by Silver-Containing Tricalcium Phosphate Microspheres. Reviewed International journal

Michiyo Honda, Yusuke Kawanobe, Kohei Nagata, Ken Ishii, Morio Matsumoto, Mamoru Aizawa

International journal of molecular sciences   21 ( 11 )   2020.5

Development of nitrogen-doped hydroxyapatite ceramics Reviewed

Nao Kaneko, Yuhei Suzuki, Ryo Umeda, Ryota Namiki, Chihiro Izawa, Tomoko Ikeda Fukazawa, Michiyo Honda, Takahiro Takei, Tomoaki Watanabe, Mamoru Aizawa

JOURNAL OF ASIAN CERAMIC SOCIETIES   8 ( 1 )   130 - 137   2020.1

Antimicrobial Activity of Protamine-Loaded Calcium Phosphates against Oral Bacteria. Reviewed International journal

Masashi Fujiki, Kodai Abe, Tohru Hayakawa, Takatsugu Yamamoto, Mana Torii, Keishi Iohara, Daisuke Koizumi, Rie Togawa, Mamoru Aizawa, Michiyo Honda

Materials (Basel, Switzerland)   12 ( 17 )   2019.9

Acceleration of Osteogenesis via Stimulation of Angiogenesis by Combination with Scaffold and Connective Tissue Growth Factor Reviewed

Michiyo Honda, Ryo Hariya, Morio Matsumoto, Mamoru Aizawa

MATERIALS   12 ( 13 )   2019.7

Acceleration of Osteogenesis via Stimulation of Angiogenesis by Combination with Scaffold and Connective Tissue Growth Factor. Reviewed International journal

Michiyo Honda, Ryo Hariya, Morio Matsumoto, Mamoru Aizawa

Materials (Basel, Switzerland)   12 ( 13 )   2019.6

Elucidation of Racemization Process of Azaspirene Skeleton in Neutral Aqueous Media Reviewed

Hirasawa Shun, Mukai Ken, Sakai Shinnosuke, Wakamori Shinnosuke, Hasegawa Takahiro, Souma Kazunori, Kanomata Nobuhiro, Ogawa Narihito, Aizawa Mamoru, Emoto Makoto

JOURNAL OF ORGANIC CHEMISTRY   83 ( 23 )   14457 - 14464   2018.12

Effect of the pore structure of an apatite-fiber scaffold on the differentiation of P19.CL6 cells into cardiomyocytes. Reviewed

Ichikawa Yuzuha, Yasuda Kei, Takahara Masahiro, Aizawa Mamoru, Kanzawa Nobuyuki

Key Eng Mater   782   116 - 123   2018.11

Preparation of anti-decay self-setting paste of hydroxyapatite/collagen utilizing (3-glycidoxypropyltrimethoxysilane) Reviewed

Taira Sato, Yuki Shirosaki, Masaki Nagaya, Yoshinori Asano, Kazuaki Nakano, Hiroshi Nagashima, Mamoru Aizawa, Masanori Kikuchi

Journal of Asian Ceramic Societies   6 ( 4 )   322 - 331   2018.10

Fabrication of chelate-setting α-tricalcium phosphate cement using sodium citrate and sodium alginate as mixing solution and its in vivo osteoconductivity. Reviewed International journal

Toshiisa Konishi, Poon Nian Lim, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Eng San Thian, Mamoru Aizawa

Journal of biomedical materials research. Part B, Applied biomaterials   106 ( 6 )   2361 - 2370   2018.8

Fabrication of chelate-setting alpha-tricalcium phosphate cement using sodium citrate and sodium alginate as mixing solution and its in vivo osteoconductivity Reviewed

Toshiisa Konishi, Poon Nian Lim, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Eng San Thian, Mamoru Aizawa

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS   106 ( 6 )   2361 - 2370   2018.8

Fabrication and biological evaluation of hydroxyapatite ceramics including bone minerals

Tomohiro Yokota, Takuya Miki, Michiyo Honda, Tomoko Ikeda-Fukazawa, Ken Ishii, Morio Matsumoto, Mamoru Aizawa

Journal of the Ceramic Society of Japan   126 ( 2 )   99 - 108   2018.2

Bioresorbability of chelate-setting calcium-phosphate cement hybridized with gelatin particles using a porcine tibial defect model Reviewed

Keishi Kiminami, Kohei Nagata, Toshiisa Konishi, Minori Mizumoto, Michiyo Honda, Kazuaki Nakano, Masaki Nagaya, Hidetoshi Arimura, Hiroshi Nagashima, Mamoru Aizawa

Journal of the Ceramic Society of Japan   126 ( 2 )   71 - 78   2018.2

Validity check of easy-to-use torsion test method forbioceramics

Journal of Asian Ceramic Societies   2018.2

In vivo evaluation of porous hydroxyapatite ceramics including bone minerals using pig model Reviewed

Tomohiro Yokota, Kazuaki Nakano, Masaki Nagaya, Michiyo Honda, Hiroshi Nagashima, Mamoru Aizawa

MATERIALS TECHNOLOGY   33 ( 10 )   689 - 697   2018

Effects of Adding Polysaccharides and Citric Acid into Sodium Dihydrogen Phosphate Mixing Solution on the Material Properties of Gelatin-Hybridized Calcium-Phosphate Cement Reviewed

Keishi Kiminami, Toshiisa Konishi, Minori Mizumoto, Kohei Nagata, Michiyo Honda, Hidetoshi Arimura, Mamoru Aizawa

MATERIALS   10 ( 8 )   2017.8

Injectable chelate-setting hydroxyapatite cement prepared by using chitosan solution: Fabrication, material properties, biocompatibility, and osteoconductivity Reviewed

Toshiisa Konishi, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Eng San Thian, Mamoru Aizawa

JOURNAL OF BIOMATERIALS APPLICATIONS   31 ( 10 )   1319 - 1327   2017.5

Morphological and functional changes in RAW264 macrophage-like cells in response to a hydrated layer of carbonate-substituted hydroxyapatite Reviewed

Kazuki Igeta, Yuta Kuwamura, Naohiro Horiuchi, Kosuke Nozaki, Daichi Shiraishi, Mamoru Aizawa, Kazuaki Hashimoto, Kimihiro Yamashita, Akiko Nagai

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A   105 ( 4 )   1063 - 1070   2017.4

Preparation of hydroxyapatite/collagen injectable bone paste with an anti-washout property utilizing sodium alginate. Part 1: influences of excess supplementation of calcium compounds Reviewed

Taira Sato, Masanori Kikuchi, Mamoru Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   28 ( 3 )   1 - 7   2017.3

Evaluation of resistance to fragmentation of injectable calcium-phosphate cement paste using X-ray microcomputed tomography Reviewed

Kohei Nagata, Kei Fujioka, Toshiisa Konishi, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   125 ( 1 )   1 - 6   2017.1

Hydrothermal synthesis of single-crystal alpha-tristrontium phosphate particles Reviewed

Akihiro Ishida, Shigeo Hori, Toshihiko Tani, Tomoko Ikeda-Fukazawa, Mamoru Aizawa

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY   37 ( 1 )   351 - 357   2017.1

Influences of combined supplementation of calcium citrate and calcium carbonate on injectable and anti-washout hydroxyapatite/collagen bone paste utilizing sodium alginate Reviewed

Naga Vijaya Lakshmi Manchinasetty, Taira Sato, Mamoru Aizawa, Sridharan Madanagurusamy, Masanori Kikuchi

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   125 ( 7 )   579 - 583   2017

Synthesis of Calcium Phosphate Microspheres Using an Ultrasonic Spray-Pyrolysis Technique and Their Application as Novel Anti-Angiogenic Chemoembolization Agents for Cancer Treatment Reviewed

Mamoru Aizawa, Michiyo Honda, Makoto Emoto

ADVANCES IN BIOINSPIRED AND BIOMEDICAL MATERIALS, VOL 2   1253   107 - 121   2017

Preparation and characterization of β-Tricalcium phosphate powders with high solubility for chelate-setting calcium-phosphate cements Reviewed

Kohei Nagata, Toshiisa Konishi, Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   758   194 - 198   2017

種々の気孔形成材を添加したキレート硬化型β-リン酸三カルシウム多孔質セメントの作製とその評価 Reviewed

J. Soc. Inorg. Mater.   24   57 - 62   2017

Histological evaluations of apatite-fiber scaffold cultured with mesenchymal stem cells by implantation at rat subcutaneous tissue Reviewed

Kitaru Suzuki, Kohei Nagata, Tomohiro Yokota, Michiyo Honda, Mamoru Aizawa

BIO-MEDICAL MATERIALS AND ENGINEERING   28 ( 1 )   57 - 64   2017

Fabrication of sodium-substituted hydroxyapatite ceramics via ultrasonic spray-pyrolysis route and their material properties Reviewed

Tomohiro Yokota, Rina Ito, Yusuke Shimizu, Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   758   166 - 171   2017

Fabrication of Potassium-Substituted Hydroxyapatite Ceramics via Ultrasonic Spray-Pyrolysis Route Reviewed

Tomohiro Yokota, Michiyo Honda, Mamoru Aizawa

Phosphorus Res. Bull   33   35 - 40   2017

Fabrication and characterization of chelate-setting β-tricalcium phosphate cements with enhanced bioresorbability Reviewed

Kohei Nagata, Toshiisa Konishi, Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   720   157 - 161   2017

Effects of Addition of alpha-Tricalcium Phosphate Powders on Material Properties of the Chelate-setting Hydroxyapatite Cement Reviewed

Kiminami Keishi, Matsuoka Kento, Konishi Toshiisa, Mizumoto Minori, Honda Michiyo, Arimura Hidetoshi, Aizawa Mamoru

Phosphorus Res. Bull.   33   7 - 13   2017

Control of Ca/P molar ratio of plate-shaped hydroxyapatite powders with an a(b)-axis orientation and their thermal stability Reviewed

Y. Mori, M. Aizawa

Int. J. Metall. Mater. Eng   3   2017

Preliminary study for co-culture of osteoblasts and endothelial cells to construct the regenerative bone Reviewed

Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   758   269 - 272   2017

Chemical state of nitrogen in nitrogen-doped hydroxyapatite ceramics with enhanced bioactivity Reviewed

R. Namiki, T. Suyama, C. Izawa, T. Ikeda-Fukazawa, M. Honda, T. Watanabe, M. Aizawa

Key Engineering Materials   720   215 - 218   2017

Microwave-Assisted Fabrication of Poly (L-lactic acid)/ Hydroxyapatite Composites as Artificial Bone Materials Invited Reviewed

Yuko Takeoka, Kaori Arai, Masahiro Yoshizawa-Fujita, Mamoru Aizawa, Masahiro Rikukawa

Journal of Microbiology and Biotechnology   5 ( 3 )   1 - 4   2016.10

Delayed Propionibacterium acnes surgical site infections occur only in the presence of an implant. Reviewed

Shiono, Y, Ishii, K, Nagai, S, Kakinuma, H, Sasaki, A, Funao, H, Kuramoto, T, Yoshioka, K, Ishihama, H, Isogai, N, Tskeshima, K, Tsuji, T, Okada, Y, Koyasu, S, Nakamura, M, Toyama, Y, Aizawa, M, Matsumoto, M

Sci. Rep.   6:   32758   2016.9

A novel hydroxyapatite film coated with ionic silver via inositol hexaphosphate chelation prevents implant-associated infection

Funao Haruki, Nagai Shigenori, Sasaki Aya, Hoshikawa Tomoyuki, Tsuji Takashi, Okada Yasunori, Koyasu Shigeo, Toyama Yoshiaki, Nakamura Masaya, Aizawa Mamoru, Matsumoto Morio, Ishii Ken

Scientific Reports   6   2016.3

Preparation of Spherical Zn-Substituted Tricalcium Phosphate Powder by Ultrasonic Spray-Pyrolysis Technique and Its Characterization Reviewed

Hiroki Nishikawa, Michiyo Honda, Tomohiro Yokota, Yusuke Shimizu, Mamoru Aizawa

JOURNAL OF NANOMATERIALS   2016

Studies on connexin 43, a gap-junction protein, in P19 embryonal carcinoma cells after culture on an apatite fiber scaffold Reviewed

Nobuyuki Kanzawa, Hiroki Takano, Kei Yasuda, Masahiro Takahara, Mamoru Aizawa

Key Engineering Materials   696   230 - 233   2016

On-site quantitation of arsenic in drinking water by disk solid-phase extraction/mobile X-ray fluorescence spectrometry

Kenta Hagiwara, Yuya Koike, Mamoru Aizawa, Toshihiro Nakamura

Talanta   144   788 - 792   2015.11

Development of a Novel Tissue Adhesive Consisting of Carboxymethylated Chitosan and Citric Acid Derivative with Active Ester Groups Reviewed

Tetsushi TAGUCHI, Hiroyuki KOBAYASHI, Hirofumi SAITO, Yoshiyuki UCHIDA, Mamoru AIZAWA

JOURNAL OF THE ADHESION SOCIETY OF JAPAN(日本接着学会誌)   43 ( 8 )   307 - 312   2015.4

Speciation of inorganic arsenic in drinking water by wavelength-dispersive X-ray fluorescence spectrometry after in situ preconcentration with miniature solid-phase extraction disks Reviewed

Kenta Hagiwara, Tetsuo Inui, Yuya Koike, Mamoru Aizawa, Toshihiro Nakamura

TALANTA   134   739 - 744   2015.3

In situ preparation of poly(L-lactic acid-co-glycolic acid)/hydroxyapatite composites as artificial bone materials (Special Issue : Fusion Materials : Creative development of materials and exploration of their function through molecular control)

Yuko Takeoka, Miki Hayashi, Nami Sugiyama, Masahiro Yoshizawa-Fujita, Mamoru Aizawa, Masahiro Rikukawa

Polymer Journal   47 ( 2 )   164 - 170   2015.2

Antibacterial polyetheretherketone implants immobilized with silver ions based on chelate-bonding ability of inositol phosphate: Processing, material characterization, cytotoxicity, and antibacterial properties Reviewed

H. Kakinuma, K. Ishii, H. Ishihama, M. Honda, Y. Toyama, M. Matsumoto, M. Aizawa

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A   103 ( 1 )   57 - 64   2015.1

In vivo evaluation of chelate-Setting cement fabricated from hydroxyapatite including bone minerals using a rabbit's tibia model

Aizawa Mamoru, Chibu Yuki, Nagata Kohei, Konishi Toshiisa, Ishii Ken, Funao Haruki, Toyama Yoshiaki, Matsumoto Morio, Honda Michiyo

402 - 407   2015

Real-Time evaluation of the effects of dexamethasone on osteoblasts using dual labeling with fluorescent probes Reviewed

Hitomi Ohsugi, Junichi Hatsukawa, Masahiro Takahara, Mamoru Aizawa, Nobuyuki Kanzawa

Key Engineering Materials   631   379 - 383   2015

Biocompatibility of silver-Containing calcium-Phosphate cements with anti-Bacterial properties Reviewed

Yusuke Shimizu, Yusuke Kawanobe, Toshiisa Konishi, Nobuyuki Kanzawa, Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   631   107 - 112   2015

Preparation of α-Tricalcium Phosphate Powders Surface-modified with Inositol Phosphate for Cement Fabrication Reviewed

Toshiisa Konishi, Michiyo Honda, Tomohiko Yoshioka, Satoshi Hayakawa, Mamoru Aizawa

Key Engineering Materials   631   113 - 118   2015

Development of bioresorbable calcium-Phosphate cements hybridized with gelatin particles and their in vivo evaluation using pig's tibia model Reviewed

Keishi Kiminami, Kento Matsuoka, Kohei Nagata, Toshiisa Konishi, Michiyo Honda, Gota Hayashida, Kazuaki Nakano, Masaki Nagaya, Hidetoshi Arimura, Hiroshi Nagashima, Mamoru Aizawa

Key Engineering Materials   631   397 - 401   2015

Interlaboratory studies on in vitro test methods for estimating in vivo resorption of calcium phosphate ceramics Reviewed

Ito Atsuo, Sogo Yu, Yamazaki Atsushi, Aizawa Mamoru, Osaka Akiyoshi, Hayakawa Satoshi, Kikuchi Masanori, Yamashita Kimihiro, Tanaka Yumi, Tadokoro Mika, de Sena Lidia Agata, Buchanan Fraser, Ohgushi Hajime, Bohner Marc

Acta Biomaterialia   25 ( NA )   347 - 355   2015

Biocompatibility of silver-containing calcium-phosphate cements with anti-bacterial properties

Yusuke Shimizu, Yusuke Kawanobe, Toshiisa Konishi, Nobuyuki Kanzawa, Michiyo Honda, Mamoru Aizawa

Key Engineering Materials   631   107 - 112   2014.11

Real-time evaluation of the effects of dexamethasone on osteoblasts using dual labeling with fluorescent probes. Reviewed

Hitomi Ohsugi, Junichi Hatsukawa, Masahiro Takahara, Mamoru Aizawa, Nobuyuki Kanzawa

Key Engineering Materials   631   379 - 383   2014.11

P19.CL6 Cells Cultured in Apatite-Fiber Scaffold Differentiate into Cardiomyocytes Reviewed

Kei Yasuda, Hide Ishii, Masahiro Takahara, Mamoru Aizawa, Nobuyuki Kanzawa

Key Engineering Materials   631   295 - 299   2014.11

Neutron Diffraction of Ice in Hydrogels Reviewed

Yurina Sekine, Tomoko Ikeda-Fukazawa, Mamoru Aizawa, Riki Kobayashi, Songxue Chi, Jaime A. Fernandez-Baca, Hiroki Yamauchi, Hiroshi Fukazawa

JOURNAL OF PHYSICAL CHEMISTRY B   118 ( 47 )   13453 - 13457   2014.11

Fabrication of apatie-fiber scaffolds with enhanced mechanical property using chemical cross-linking of type I-collagen and their biocompatibility. Reviewed

Satoshi MOTOJIMA, Naoko IGETA, Hiroki MURAMATSU, Hiroshi UCHIDA, Kiyoshi ITATANI, Nobuyuki KANZAWA, Michiyo HONDA, Mamoru AIZAWA

Journal of the Society of Inorganic Materials, Japan   21 ( 372 )   278 - 285   2014.9

A Novel Mouse Model of Soft-Tissue Infection Using Bioluminescence Imaging Allows Noninvasive, Real-Time Monitoring of Bacterial Growth Reviewed

Kenji Yoshioka, Ken Ishii, Tetsuya Kuramoto, Shigenori Nagai, Haruki Funao, Hiroko Ishihama, Yuta Shiono, Aya Sasaki, Mamoru Aizawa, Yasunori Okada, Shigeo Koyasu, Yoshiaki Toyama, Morio Matsumoto

PLOS ONE   9 ( 9 )   e106367   2014.9

The response of RAW 264 macrophage on carbonated hydroxyapatite

Annual Reports of the Institute of Biomaterials and Bioengineering   48   14 - 16   2014

Fabrication of anti-bacterial cement using calcium-phosphate microspheres loaded with vancomycin and its drug release.

Mochida N, Kawanobe Y, Honda M, Konish T, Mizumoto M, Habuto Y, Knazawa N, Aizawa M

Arch. BioCeram. Res.   13   140 - 141   2013.12

In vitro and in vivo antimicrobial properties of silver-containing hydroxyapatite prepared via ultrasonic spray pyrolysis route Reviewed

Honda Michiyo, Kawanobe Yusuke, Ishii Ken, Konishi Toshiisa, Mizumoto Minori, Kanzawa Nobuyuki, Matsumoto Morio, Aizawa Mamoru

Materials Science and Engineering: C   33 ( 8 )   5008 - 5018   2013.12

Selective differentiation of bone marrow-derived mesenchymal stromal cells into osteocytes via endochondral ossification in an apatite-fiber scaffold Reviewed

Michiyo Honda, Yuka Watanabe, Takahide Tsuchiya, Nobuyuki Kanzawa, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   121 ( 1417 )   759 - 765   2013.9

Preparation of injectable hydroxyapatite/collagen paste using sodium alginate and influence of additives Reviewed

Taira Sato, Akinori Kochi, Yuki Shirosaki, Satoshi Hayakawa, Mamoru Aizawa, Akiyoshi Osaka, Masanori Kikuchi

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   121 ( 1417 )   775 - 781   2013.9

Effects of crosslinker density on the polymer network structure in poly-N,N-dimethylacrylamide hydrogels Reviewed

Ikeda-Fukazawa Tomoko, Ikeda Naohiro, Tabata Mayu, Hattori Masataka, Aizawa Mamoru, Yunoki Shunji, Sekine Yurina

JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS   51 ( 13 )   1017 - 1027   2013.7

Selective differentiation of bone marrow-derived mesenchymal stromal cells into osteocytes via endochondral ossification in an apatite-fiber scaffold.

Honda M, Watanabe Y, Tsuchiya T, Kanzawa N, Aizawa M

Journal of the Ceramic Society of Japan   121 ( 1417 )   759 - 765   2013.7

Biodegradable β-tricalcium phosphate cement with anti-washout property based on chelate-setting mechanism of inositol phosphate Reviewed

Toshiisa Konishi, Shuhei Takahashi, Zhi Zhuang, Kohei Nagata, Minori Mizumoto, Michiyo Honda, Yasuhiro Takeuchi, Hitomi Matsunari, Hiroshi Nagashima, Mamoru Aizawa

Journal of Materials Science: Materials in Medicine   24 ( 6 )   1383 - 1394   2013.6

DNA-templated Fabrication of Biphasic Calcium Phosphate Ceramics with a Bimodal Pore Structure for Tissue Engineering Reviewed

Nami Sugiyama, Yusuke Yanagi, Masahiro Yoshizawa-Fujita, Mamoru Aizawa, Yuko Takeoka, Masahiro Rikukawa

CHEMISTRY LETTERS   42 ( 5 )   465 - 467   2013.5

Development of a,b-plane-oriented hydroxyapatite ceramics as models for living bones and their cell adhesion behavior Reviewed

Zhi Zhuang, Takahiko J. Fujimi, Mariko Nakamura, Toshiisa Konishi, Hideyuki Yoshimura, Mamoru Aizawa

ACTA BIOMATERIALIA   9 ( 5 )   6732 - 6740   2013.5

Protein adsorption on single-crystal hydroxyapatite particles with preferred orientation to a(b)- and c-axes Reviewed

Zhi Zhuang, Mamoru Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   24 ( 5 )   1211 - 1216   2013.5

Noncovalent functionalization of boron nitride nanotubes using water-soluble synthetic polymers and the subsequent preparation of superhydrophobic surfaces Reviewed

Zhenghong Gao, Kei Fujioka, Toshiki Sawada, Chunyi Zhi, Yoshio Bando, Dmitri Golberg, Mamoru Aizawa, Takeshi Serizawa

POLYMER JOURNAL   45 ( 5 )   567 - 570   2013.5

Noncovalent functionalization of boron nitride nanotubes using water-soluble synthetic polymers and the subsequent preparation of superhydrophobic surfaces

Zhenghong Gao, Kei Fujioka, Toshiki Sawada, Chunyi Zhi, Yoshio Bando, Dmitri Golberg, Mamoru Aizawa, Takeshi Serizawa

POLYMER JOURNAL   45 ( 5 )   567 - 570   2013.5

人工骨材料への応用を目指したポリ(L-乳酸)/水酸アパタイト複合体のIn-situ合成 Reviewed

杉山奈未, 大野達也, 國分玲子, 相澤守, 竹岡裕子, 陸川政弘

高分子論文集   70 ( 5 )   185 - 192   2013.4

Novel chelate-setting calcium-phosphate cements fabricated with wet-synthesized hydroxyapatite powder

Toshiisa Konishi, Yukiko Horiguchi, Minori Mizumoto, Michiyo Honda, Kazuya Oribe, Hikaru Morisue, Ken Ishii, Yoshiaki Toyama, Morio Matsumoto, Mamoru Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   24 ( 3 )   611 - 621   2013.3

Novel chelate-setting calcium-phosphate cements fabricated with wet-synthesized hydroxyapatite powder Reviewed

Toshiisa Konishi, Yukiko Horiguchi, Minori Mizumoto, Michiyo Honda, Kazuya Oribe, Hikaru Morisue, Ken Ishii, Yoshiaki Toyama, Morio Matsumoto, Mamoru Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   24 ( 3 )   611 - 621   2013.3

生体内で優れた抗菌効果をもつ新規合成樹脂製インプラントの開発

石濱 寛子, 石井 賢, 永井 重徳, 柿沼 祐亮, 佐々木 文, 蔵本 哲也, 吉岡 研之, 船尾 陽生, 相澤 守, 岡田 保典, 小安 重夫, 戸山 芳昭, 松本 守雄

Journal of Spine Research   4 ( 3 )   502 - 502   2013.3

Zinc-substituted hydroxyapatite: A biomaterial with enhanced bioactivity and antibacterial properties

E. S. Thian, T. Konishi, Y. Kawanobe, P. N. Lim, C. Choong, B. Ho, M. Aizawa

Journal of Materials Science: Materials in Medicine   24 ( 2 )   437 - 445   2013.2

Adsorption Behavior of Sodium Inositol Hexaphosphate on the Surface of Hydroxyapatite

Toshiisa Konishi, Minori Mizumoto, Michiyo Honda, Mamoru Aizawa

BIOCERAMICS 24   529-530   161 - 166   2013

In situ Preparation of Poly(L-lactic acid)/hydroxyapatite Composites as Artificial Bone Materials

Nami Sugiyama, Tatsuo Ohno, Kunibu Ryoko, Mamoru Aizawa, Yuko Takeoka, Masahiro Rikukawa

KOBUNSHI RONBUNSHU   70 ( 5 )   185 - 192   2013

Fabrication of novel biodegradable α-tricalcium phosphate cement set by chelating capability of inositol phosphate and its biocompatibility

Konishi Toshiisa, Mizumoto Minori, Honda Michiyo, Horiguchi Yukiko, Oribe Kazuya, Morisue Hikaru, Ishii Ken, Toyama Yoshiaki, Matsumoto Morio, Aizawa Mamoru

Journal of Nanomaterials   2013   2013

Three-dimentional Culture of Vascular Endothelial Cells Using Vascular Endothelial Growth Factor-loaded Apatite-fiber Scaffolds with Enhanced Mechanical Property

K. Kayashima, R. Oyama, M. Emoto, H. Maehashi, T. Matsuura, M. Aizawa

BIOCERAMICS 24   529-530   402 - +   2013

Studies on the Anti-Tumor Action of Chelate-Setting Apatite Cements

Tetsuya Inayama, Hidenori Konishi, Mamoru Aizawa, Nobuyuki Kanzawa

BIOCERAMICS 24   529-530   178 - +   2013

Reconstruction of tissue-engineered bone using an apatite-fiber scaffold, rat bone marrow cells and radial-flow bioreactor: Optimization of flow rate in circulating medium

Maiko Miura, Jun Fukasawa, Yumiko Yasutomi, Haruka Maehashi, Tomokazu Matsuura, Mamoru Aizawa

Key Engineering Materials   529-530 ( 1 )   397 - 401   2013

Morphological Control of Hydroxyapatite Particles by Homogeneous Precipitation Method in the Co-Presence of Various Carboxylic Acids

Hideki Shimizu, Zhi Zhuang, Mamoru Aizawa

BIOCERAMICS 24   529-530   61 - 65   2013

In Vitro evaluation of silicon-containing apatite fiber scaffolds for bone tissue engineering

Y. Kinoshita, S. M. Best, M. Aizawa

BIOCERAMICS 24   529-530   391 - +   2013

In Vitro Evaluation of Chelate-Setting Cements Fabricated from Silicon-Containing Apatite Powder Using Osteoblastic Cells

Yusuke Nakashima, Michiyo Honda, Toshiisa Konishi, Minori Mizumoto, Mamoru Aizawa

BIOCERAMICS 24   529-530   183 - +   2013

In Vitro Biological Evaluation of Anti-Tumor Effect of the Chelate-Setting Hydroxyapatite Cement

Michiyo Honda, Toshiisa Konishi, Minori Mizumoto, Mamoru Aizawa

BIOCERAMICS 24   529-530   173 - 177   2013

Fabrications of Boron-Containing Apatite Ceramics via Ultrasonic Spray-Pyrolysis Route and Their Surface Properties

Mariko Nakamura, Zhi Zhuang, Mamoru Aizawa

BIOCERAMICS 24   529-530   109 - 113   2013

Evaluation of the Anti-Bacterial Activity of a Novel Chelate-Setting Apatite Cement Containing Lactoferrin

Hitomi Ohsugi, Yuri Habuto, Michiyo Honda, Mamoru Aizawa, Nobuyuki Kanzawa

BIOCERAMICS 24   529-530   187 - +   2013

Comparative study on bioresorbability of chelate-setting cements with various calcium-phosphate phase using rabbit model

Toshiisa Konishi, Shuhei Takahashi, Minori Mizumoto, Michiyo Honda, Koki Kida, Yukiko Horiguchi, Kazuya Oribe, Ken Ishii, Hikaru Morisue, Yoshiaki Toyama, Morio Matsumoto, Mamoru Aizawa

Key Engineering Materials   529-530 ( 1 )   167 - 172   2013

Analysis of gene expression and morphology of P19 cells cultured in an apatite-fiber scaffold

Hide Ishii, Yuya Mukai, Mamoru Aizawa, Nobuyuki Kanzawa

BIOCERAMICS 24   529-530   370 - +   2013

Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route

Michiyo Honda, Koichi Kikushima, Yusuke Kawanobe, Toshiisa Konishi, Minori Mizumoto, Mamoru Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   23 ( 12 )   2923 - 2932   2012.12

Fabrication of chelate-setting cement from hydroxyapatite powder prepared by simultaneously grinding and surface-modifying with sodium inositol hexaphosphate and their material properties

Toshiisa Konishi, Zhi Zhuang, Minori Mizumoto, Michiyo Honda, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   120 ( 1401 )   159 - 165   2012.5

Synthesis of plate-shaped hydroxyapatite via an enzyme reaction of urea with urease and its characterization

Zhi Zhuang, Hiroaki Yamamoto, Mamoru Aizawa

POWDER TECHNOLOGY   222   193 - 200   2012.5

Establishment of a Real-Time, Quantitative, and Reproducible Mouse Model of Staphylococcus Osteomyelitis Using Bioluminescence Imaging

Haruki Funao, Ken Ishii, Shigenori Nagai, Aya Sasaki, Tomoyuki Hoshikawa, Mamoru Aizawa, Yasunori Okada, Kazuhiro Chiba, Shigeo Koyasu, Yoshiaki Toyama, Mono Matsumoto

INFECTION AND IMMUNITY   80 ( 2 )   733 - 741   2012.2

Effect of the addition of various polysaccharides on the material properties and cytotoxicity of chelate-setting β-tricalcium phosphate cement

T. Konishi, S. Takahashi, M. Mizumoto, M. Honda, K. Oribe, M. Aizawa

Phosphorus Res. Bull   26   59-64   2012

Effect of flow rate of medium in radial-flow bioreactor on the differentiation of osteoblasts in tissue-engineered bone reconstructed using an apatite-fiber scaffold and rat bone marrow cells

Maiko Miura, Jun Fukasawa, Yumiko Yasutomi, Haruka Maehashi, Tomokazu Matsuura, Mamoru Aizawa

Key Engineering Materials   493-494   878 - 883   2012

Biochemical studies of the potential anti-tumor activity of novel chelate-setting apatite cements

Hidenori Konishi, Michiyo Honda, Mamoru Aizawa, Nobuyuki Kanzawa

Key Engineering Materials   493-494   315 - 319   2012

Ultrastructural Observation of Hydroxyapatite Ceramics with Preferred Orientation to a-plane Using High-resolution Transmission Electron Microscopy

Zhi Zhuang, Takuya Miki, Midori Yumoto, Toshiisa Konishi, Mamoru Aizawa

IUMRS INTERNATIONAL CONFERENCE IN ASIA 2011   36   121 - 127   2012

Ultrastructural analysis of hydroxyapatite nano-particles synthesized under different initial pH conditions using high-resolution transmission electron microscopy

Z. Zhuang, T. Konishi, H. Yoshimura, M. Aizawa

Phosphorus Res. Bull.   26   81-86   2012

Preparation of silver-containing hydroxyapatite powder by ultrasonic spray-pyrolysis technique and its antibacterial property

Yusuke Kawanobe, Michiyo Honda, Toshiisa Konishi, Minori Mizumoto, Yuri Habuto, Nobuyuki Kanzawa, Zhi Zhuang, Mamoru Aizawa

Key Engineering Materials   493-494 ( 678-683 )   678 - 683   2012

Preparation of calcium-phosphate microspheres by salt-assisted ultrasonic spray-pyrolysis technique and their drug release behavior using anti-angiogenic agent, TNP-470

Masaru Matsueda, Makoto Emoto, Mamoru Aizawa

Key Engineering Materials   493-494   672 - 677   2012

In vivo biocompatibility of apatite-fiber scaffold with enhanced mechanical property using pig model by implanting into tibia

T. Ganmoto, M. Honda, T. Konishi, M. Mizumoto, H. Matsunari, Y. Takeuchi, H. Nagashima

Phosphorus Res. Bull   26   1-3   2012

In vitro bioresorbability of chelate-setting cemetns with various calcium-phosphate phases

H. Manabe, T. Konishi, M. Mizumoto, M. Honda

Phosphorus Res. Bull   26   105-108   2012

Hydroxyapatite ceramics including bone minerals promote differentiation of osteoblasts derived from rat bone marrow cells

Mamoru Aizawa, Takuya Miki, Yumiko Yasutomi, Michiyo Honda, Hideyuki Yoshimura

Key Engineering Materials   493-494   320 - 324   2012

Fabrication of organic/inorganic hybrids by infiltration of commercially-available PLGA into porous hydroxyapatite ceramics and its material properties

Naoki Osada, Yusuke Shigemitsu, Masashi Makita, Kazuya Oribe, Mamoru Aizawa

Key Engineering Materials   493-494   556 - 560   2012

Fabrication of Chelate-setting Cements from Hydroxyapatite Powders Surface-modified with Various Sodium Inositol Hexaphosphate Concentrations and their Mechanical Properties

Toshiisa Konishi, Minori Mizumoto, Michiyo Honda, Zhi Zhuang, Mamoru Aizawa

IUMRS INTERNATIONAL CONFERENCE IN ASIA 2011   36   137 - 143   2012

Fabrication of chelate-setting cement using silicon-substituted hydroxyapatite and its property

Y. Nakashima, M. Honda, T. Konishi, M. Mizumoto, M. Aizawa

Key Engineering Materials   493-494   370 - 374   2012

Fabrication and evaluation of silicon-containing apatite fiber scaffolds for bone tissue engineering

Y. Kinoshita, S. M. Best

Phosphorus Res. Bull   26   101-104   2012

Synthesis of Uniform and Dispersive Calcium Carbonate Nanoparticles in a Protein Cage through Control of Electrostatic Potential

Hiroko Fukano, Takuya Takahashi, Mamoru Aizawa, Hideyuki Yoshimura

INORGANIC CHEMISTRY   50 ( 14 )   6526 - 6532   2011.7

Detection of Kinase Activity Using a Synthetic System of Gold Nanoparticles in HEPES Buffer

Toshiki Sawada, Naoto Shirakawa, Yu Hirai, Mineo Hashizume, Mamoru Aizawa, Takeshi Serizawa

CHEMISTRY LETTERS   40 ( 2 )   142 - 143   2011.2

Fabrication of novel bioresorbable beta-tricalcium phosphate cement on the basis of chelate-setting mechanism of inositol phosphate and its evaluation

Shuhei Takahashi, Toshiisa Konishi, Koji Nishiyama, Minori Mizumoto, Miehiyo Honda, Yukiko Horiguchi, Kazuya Oribe, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   119 ( 1385 )   35 - 42   2011.1

Transplantation of Liver Organoids in the Omentum and Kidney

Ryota Saito, Yuji Ishii, Ryusuke Ito, Keisuke Nagatsuma, Ken Tanaka, Masaya Saito, Haruka Maehashi, Hideki Nomoto, Kiyoshi Ohkawa, Hiroshi Mano, Mamoru Aizawa, Hiroshi Hano, Katsuhiko Yanaga, Tomokazu Matsuura

ARTIFICIAL ORGANS   35 ( 1 )   80 - U153   2011.1

Fabrication of cement specimens from hydroxyapatite powders surface-modified with various concentrations of sodium inositol hexaphosphate and their evaluation

KONISHI TOSHIISA, MIZUMOTO MINORI, HONDA MICHIYO, AIZAWA MAMORU

Preprints of Annual Meeting of The Ceramic Society of Japan<br> Preprints of Fall Meeting of The Ceramic Society of Japan   2011F   153 - 153   2011

Preparation of Apatite Microspheres with Nano-Size Pores on the Surface via Salt-Assisted Ultrasonic Spray-Pyrolysis Technique and its Drug Release Behavior

Y. Kawanobe, M. Honda, T. Konishi, M. Mizumoto, Y. Habuto, N. Kanzawa, T. Uchino, M. Aizawa

JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY   47 ( 1 )   6 - 10   2011

Micro-CT of Porous Apatite Fiber Scaffolds Studied by Projection X-ray Microscopy Reviewed

J. Moriya, M. Aizawa, H. Yoshimura

10TH INTERNATIONAL CONFERENCE ON X-RAY MICROSCOPY   1365   407 - 410   2011

Fabrication of calcium-phosphate cements from hydroxyapatite powders surface-modified with various concentrations of sodium inositol hexaphosphate and their material properties

T. Konishi, M. Mizumoto, M. Honda, Z. Zhuang, M. Aizawa

World Journal of Engineering   Supplement 1   595-596   2011

Changes of Material Properties of Inorganic/Organic Hybrids Fabricated by Infiltration of Poly(L-Lactic Acid) Into Open Pores of Porous Hydroxyapatite Ceramics in a Simulated Body Fluid

T. Yoshimi, N. Sugiyama, Y. Takeoka, M. Rikukawa, K. Oribe, M. Aizawa

JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY   47 ( 1 )   18 - 22   2011

Cell Proliferation, Morphology and Differentiation of Transgenic-Cloned Pig Calvarial Osteoblasts on the Silicon-Substituted Hydorxyapatite Ceramics Fabricated via Ultrasonic Spray-Pyrolysis Technique

M. Honda, K. Kikushima, T. Konishi, M. Mizumoto, H. Matsunari, H. Nagashima, M. Aizawa

JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY   47 ( 1 )   37 - 41   2011

Fabrication of biodegradable beta-tricalcium phosphate/poly(L-lactic acid) hybrids and their in vitro biocompatibility

Yusuke Shigemitsu, Nami Sugiyama, Kazuya Oribe, Masahiro Rikukawa, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   118 ( 1384 )   1181 - 1187   2010.12

Topographical analyses of proliferation and differentiation of osteoblasts in micro- and macropores of apatite-fiber scaffold

Michiyo Honda, Takahiko J. Fujimi, Shigeki Izumi, Kouji Izawa, Mamoru Aizawa, Hikaru Morisue, Takahide Tsuchiya, Nobuyuki Kanzawa

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A   94A ( 3 )   937 - 944   2010.9

生体内で優れた抗菌活性を有するインプラントの開発

船尾 陽生, 石井 賢, 永井 重徳, 佐々木 あや, 干川 智之, 相澤 守, 岡田 保典, 千葉 一裕, 小安 重夫, 戸山 芳昭, 松本 守雄

日本整形外科学会雑誌   84 ( 8 )   S1157 - S1157   2010.8

Novel chemoembolization using calcium-phosphate ceramic microsphere incorporating TNP-470, an anti-angiogenic agent

Makoto Emoto, Yasuko Naganuma, Batsuren Choijamts, Toshiki Ohno, Hajime Yoshihisa, Nobuhiko Kanomata, Tatsuhiko Kawarabayashi, Mamoru Aizawa

CANCER SCIENCE   101 ( 4 )   984 - 990   2010.4

The effect of timing in the administration of hepatocyte growth factor to modulate BMP-2-induced osteoblast differentiation Reviewed

Toshiki Kawaski, Yasuo Niki, Takeshi Miyamoto, Keisuke Horiuchi, Morio Matsumoto, Mamoru Aizawa, Yoshiaki Toyama

BIOMATERIALS   31 ( 6 )   1191 - 1198   2010.2

Anticancer efficacy on chelate-setting apatite cement - A fundamental study on human osteosarcoma -

Honda Michiyo, Mizumoto Minori, Kanzawa Nobuyuki, Aizawa Mamoru

Preprints of Annual Meeting of The Ceramic Society of Japan<br> Preprints of Fall Meeting of The Ceramic Society of Japan   2010S   1E30 - 1E30   2010

Development of Biocompatible Apatite Sheets with Various Ca/P Ratios and Carbonate Ion Contents for Mouse Osteoblastic Cell Culture and their Evaluation

H. Ueno, T. J. Fujimi, Okada, I, M. Aizawa

JOURNAL OF THE AUSTRALIAN CERAMIC SOCIETY   46 ( 2 )   14 - 18   2010

Negative modulation of BMP-2-induced osteoblast differentiation by HGF is affected by the timing of HGF administration

T. Kawasaki, Y. Niki, T. Miyamoto, K. Horiuchi, M. Matsumoto, M. Aizawa, Yoshiaki Toyama

Biomaterials   31   1191-1198   2010

Synthesis of calcium-phosphate microsphere by salt-assisted ultrasonic spray-pyrolysis technique and its drug release

M. Matsueda, H. Yoshihisa, M. Emoto, M. Aizawa

Archives of BioCeramics Research   10   137-140   2010

Selective Adsorption Behaviors of Proteins on Hydroxyapaties of Different Morphology

Z. Zhuang, M. Aizawa

Archives of BioCeramics Research   10   153-156   2010

Fabrication of chelate-setting β-tricalcium phosphate cements for minimally-invasive treatment and their evaluations

S. Takahashi, T. Konishi, K. Nishiyama, M. Mizumoto, M. Honda, S. Sato, K. Oribe, M. Aizawa

Archives of BioCeramics Research   10   145-148   2010

Effects of mixing solutions on the initial setting time and compressive strength of Chelate-setting Apatite Cements

S. Sato, Y. Horiguti, M. Mizumoto, T. Konishi, M. Honda, K. Oribe, M. Aizawa

Archives of BioCeramics Research   10   133-136   2010

Detection of enzyme activities based on the synthesis of gold nanoparticles in HEPES buffer

Takeshi Serizawa, Yu Hirai, Mamoru Aizawa

MOLECULAR BIOSYSTEMS   6 ( 9 )   1561 - 1564   2010

Chemical composition and ultrastructure of apatite ceramics including bone minerals

T. Miki, T. Fujino, Y. Yasutomi, T. Fukazawa, H. Yoshimura, M. Aizawa

Archives of BioCeramics Research   10   141-144   2010

Novel Synthetic Route to Peptide-Capped Gold Nanoparticles

Takeshi Serizawa, Yu Hirai, Mamoru Aizawa

LANGMUIR   25 ( 20 )   12229 - 12234   2009.10

Novel apatite fiber scaffolds can promote three-dimensional proliferation of osteoblasts in rodent bone regeneration models Reviewed

Hikaru MORISUE, Morio MATSUMOTO, Kazuaki CHIBA, Hideo MATSUMOTO, Yoshiaki TOYAMA, Mamoru AIZAWA, Nobuyuki KANZAWA, Takahiro J. Fujimi, Hiroshi UCHIDA, Isao OKADA

Journal of Biomedical Materials Research Part A   90A ( 3 )   811 - 818   2009.9

Novel apatite fiber scaffolds can promote three-dimensional proliferation of osteoblasts in rodent bone regeneration models.

Hikaru Morisue, Morio Matsumoto, Kazuhiro Chiba, Hideo Matsumoto, Yoshiaki Toyama, Mamoru Aizawa, Nobuyuki Kanzawa, Takahiro J Fujimi, Hiroshi Uchida, Isao Okada

Journal of Biomedical Materials Research Part A   90 ( 3 )   811 - 818   2009.9

肝細胞増殖因子はBMP-2による骨芽細胞分化を抑制する Reviewed

川崎 俊樹, 二木 康夫, 宮本 健史, 堀内 圭輔, 松本 守雄, 相澤 守, 戸山 芳昭

日本整形外科学会雑誌   83 ( 8 )   S1096 - S1096   2009.8

A preliminary study on anti-tumorigenesis of chelate- setting hydroxyapatite cements using inositol phosphate

Y. Inomata, W. Hiraoka, M. Aizawa

Bioceramics   22   867-870   2009

Fabrication of chelate-setting cement using apatite powder including bone minerals and its property

T. Fujii, T. Fujino, S. Sato, K. Oribe, M. Aizawa

Bioceramics   22   875-878   2009

Effects of mixing solutions in the compressive strength and biocompatibility of chelate-setting apatite cements

S. Sato, Y. Horiguti, M. Mizumoto, K. Oribe, M. Aizawa

Archives of BioCeramics Research   9   335-338   2009

Dissolution rate of the hydroxyapatite and tricalcium fiber scaffolds in a Tris(hydroxymethyl)aminomethane-HCl buffer solution

J. Fukasawa, A. Ito, M. Aizawa

Archives of BioCeramics Research   9   251-254   2009

Development of Apatite-fiber Scaffold with Enhanced Mechanical Property via Uniaxial Pressing and Their Biocompatibility

S. Motojima, H. Morisue, M. Matsumoto, Y. Toyama, M. Aizawa

Bioceramics   22   177-180   2009

Characterization of Silicon-substituted hydroxyapatite powders Prepared by ultrasonic spray-pyrolysis technique

K. Kikushima, H. Yoshihisa, M. Aizawa

Bioceramics   22   79-82   2009

Analyses of ossification of bone marrow stromal cells on Apatite-fiber scaffold

M. Honda, Y. Watanabe, N. Kanzawa, M. Aizawa

Bioceramics   22   205-208   2009

An improved method for the measurement of alkaline phosphatase activity to analyze the bone cell differentiation

K. Yuzawa, A. Sato, M. Honda, T. Tsuchiya, M. Aizawa, N.Kanzawa

Bioceramics   22   213-216   2009

A study on the bone induction of mouse C2C12 myoblast cultured in apatite-fiber scaffold

K. Maeda, M. Honda, T. Tsuchiya, M. Aizawa, N. Kanzawa

Bioceramics   22   435-438   2009

In vitro and in vivo evaluations of chelate-setting -tricalcium phosphate cements using inositol phosphate

K. Nishiyama, S. Takahashi, K. Oribe, M. Matsumoto, H. Morisue, Y. Toyama, M. Aizawa

Bioceramics   22   871-874   2009

Three-dimentional Culture of Vascular Endothelial Cells Using Apatite-fiber Scaffolds with enhanced mechanical property

R. Oyama, S. Motojima, T. Matsuura, H. Maehashi, M. Aizawa

Bioceramics   22   201-204   2009

Three-Dimensional Structure of Apatite Fibre Scaffolds Studied by X-Ray Micro-CT

J. Moriya, M. Aizawa, H. Yoshimura

Bioceramics   22   225-228   2009

Synthesis of Plate-Shaped Hydroxyapatite with Preferred Orientation to c-Plane and its Characterization

Z. Zhuang, H. Yamamoto, M. Aizawa

Bioceramics   22   75-78   2009

Gene expression of osteoblasts cultured on apatite ceramics with preferred orientation to a-plane

Y. Murasugi, A. Miyazaki, N. Kanzawa, M. Aizawa

Bioceramics   22   431-434   2009

Fabrication of chelate-setting α-tricalcium phosphate cement with enhanced mechanical property by addition of polysaccharide into mixing solution

T. Konishi, K. Oribe, M. Aizawa

Archives of BioCeramics Research   9   363-366   2009

Fabrication of chelate-setting cements from silicon-substituted apatite powder prepared by ultrasonic spray-pyrolysis technique and its property

K. Kikushima, K. Oribe, M. Aizawa

Archives of BioCeramics Research   9   331-334   2009

Strengthening of porous -tricalcium phosphate ceramics by introducing poly-(L-lactic acid) with high-molecular-weight

Y. Shigemitsu, M. Makita, K. Oribe, M. Aizawa

Archives of BioCeramics Research   9   95-98   2009

Novel Biomaterial via infiltration of poly-Hydroxyethyl Methacylate (poly-HEMA) into Porous Hydroxyapatite Ceramics

C-w. Oh, Y. Shigemitsu, M. Aizawa

Archives of BioCeramics Research   9   359-362   2009

In Vivo Evaluation of Biodegradable -tricalcium Phosphate / poly-(L-lactic acid) Hybrids in rabbit’s tibia

Y. Iwamoto, Y. Shigemitsu, K. Oribe, N. Sugiyama, Y. Takeoka, M. Rikukawa, M. Matsumoto, H. Morisue, Y. Toyama, M. Aizawa

Bioceramics   22   639-642   2009

In vivo bone formation using three-dimensional scaffolds developed from a single crystal apatite fiber

H. Morisue, M. Matsumoto, K. Chiba, H. Matsumoto, Y. Toyama, M. Aizawa, N. Kanzawa, T. J. Fujimi, H. Uchida, I. Okada

J. Biomed. Mater. Res. A   90A   811-818   2009

In vitro evaluation of hybrids fabricated by infiltration of poly(L-lactic acid) into open pores of porous hydroxyapatite ceramics with Bimodal Pore-size Distribution using MC3T3-E1 cells

T. Yoshimi, Y. Tanaka, N. Sugiyama, Y. Takeoka, M. Rikukawa, M. Aizawa

Bioceramics   22   643-646   2009

In vitro evaluation of bioresorbability of apatite-fiber scaffolds for tissue engineering of bone and its analysis of dissolution mechanism

J. Fukasawa, A. Ito, M. Aizawa

Bioceramics   22   209-212   2009

Fabrication of chelate-setting hydroxyapatite cements from four kinds of commercially-available powder with various shape and crystallinity and their mechanical property

Yukiko Horiguchi, Akifumi Yoshikawa, Kazuya Oribe, Mamoru Aizawa

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   116 ( 1349 )   50 - 55   2008.1

Fabrication and biocompatibility of poly(L-lactide)/hydroxyapatite composites for alternative bone materials-effect of lipase introduction

Tatsuya Ohno, Nami Sugiyama, Masahiro Yoshizawa-Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

8th World Biomaterials Congress 2008   3   1662   2008

In vitro evaluation of biodegradable β-tricalcium phosphate/poly-(L- lactic acid) hybrids using osteobrastic cell

Y. Iwamoto, T. Miyashita, Y. Tanaka, N. Sugiyama, Y. Takeoka, M. Rikukawa, M. Aizawa

8th World Biomaterials Congress 2008   1   409   2008

Enhancement of the mechanical property of apatite-fiber scaffold using type I-collagen

S. Motojima, N. Igeta, M. Honda, N. Kanzawa, M. Aizawa

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   943 - +   2008

Synthesis of Highly Dispersive Ca Nanoparticles Using the Protein Shel

H. Fukano, M. Aizawa, H. Yoshimura

Archives of BioCeramics Research   8   72-75   2008

Reconstruction of liver organoid using an apatite-fiber scaffold, a radial-flow bioreactor, and FLC-4 cells of hepatocyte model

M. Aizawa, A. Hiramoto, H. Maehashi, T. Matsuura

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   1165 - +   2008

Microstructural observation of calcium-deficient single crystal apatite fibers and phase changes during heating

A. Taki, H. Yoshimura, M. Aizawa

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   147 - +   2008

Microenvironment of apatite-fiber scaffold affects cell proliferation and resulting cell differentiation

Michiyo Honda, Shigeki Izumi, Nobuyuki Kanzawa, Takahide Tsuchiya, Mamoru Aizawa

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   1075 - +   2008

In vitro synthesis of calcium nanoparticles using the protein cage of apoferritin

Hiroko Fukano, Mamoru Aizawa, Hideyuki Yoshimura

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   183 - +   2008

In vitro evaluation of bioresorbability of apatite-fiber scaffolds and -tricalciumphosphate-fiber scaffolds using an acetic acid buffer as a model of quasi-osteoclastic producting solution

J. Fukasawa, M. Aizawa

Archives of BioCeramics Research   8   189-192   2008

Fabrication of chelate-setting α-tricalcium phosphate cement with bioresorbability and its evaluation

T. Konishi, Y. Horiguchi, K. Oribe, M. Matsumoto, H. Morisue, Y. Toyama, M. Aizawa

Archives of BioCeramics Research   8   126-129   2008

Changes of Material Properties of Chelate-setting Apatite Cement in a Simulated Body Fluid

K. Kikushima, Y. Horiguchi, K. Oribe, M. Aizawa

Archives of BioCeramics Research   8   49-52   2008

Biological evaluation of chelate-setting apatite cement using inositol phosphate

K. Kida, Y. Horiguchi, K. Oribe, H. Morisue, M. Matsumoto, Y. Toyama, M. Aizawa

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   335 - +   2008

Biocompatibility of Novel Chelate-setting Apatite Cement using Inositol Phosphate

M. Aizawa, K. Kida, Y. Horiguchi, K. Oribe, H. Morisue, M. Matsumoto, Y. Toyama

Archives of BioCeramics Research   8   162-165   2008

Anti-tumorigenesis of hollow calcium-phosphate microsphere loaded with anti-angiogenic agent

M. Aizawa, T. Ohno, N. Kanomata, K. Yano, M. Emoto

BIOCERAMICS, VOL 20, PTS 1 AND 2   361-363   1215 - +   2008

Ring-opening bulk polymerization of L-lactide in porous hydroxyapatite

Nami Sugiyama, Ryoko Kunibu, Masahiro Yoshizawa-Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

CHEMISTRY LETTERS   36 ( 12 )   1476 - 1477   2007.12

Development of apatite-fiber scaffold and its application to tissue engineering of bone

Materials integration   20 ( 11 )   62 - 68   2007.11

Fabrication of Biodegradable -tricalcium Phosphate/poly-(L-lactic acid) Hybrids and Their In Vitro Evaluation

Y. Iwamoto, T. Miyashita, Y. Tanaka, N. Sugiyama, Y. Takeoka, M. Rikukawa, M. Aizawa

Archives of BioCeramics Research   7   289-292   2007

Preparation of calcium-phosphate microsphere with well-controlled particle sizes by ultrasonic spray-pyrolysis technique

H. Yoshihisa, N. Onaya, P, K. Choi, M. Aizawa

Archives of BioCeramics Research   7   185-188   2007

Preparation of apatite powder including bone minerals and its characterization

T. Fujino, M. Aizawa

Archives of BioCeramics Research   7   175-178   2007

Fabrication of chelate-setting cements from apatite powder synthesized via a wet process and its mechanical property

Y. Horiguchi, K. Oribe, M. Aizawa

Archives of BioCeramics Research   7   201-204   2007

Development of a Novel Tissue Adhesive Consisting of Carboxymethylated Chitosan and Citric Acid Derivative with Active Ester Groups

TAGUCHI Tetsushi, KOBAYASHI Hiroyuki, SAITO Hirofumi, UCHIDA Yoshiyuki, AIZAWA Mamoru

Journal of The Adhesion Society of Japan   43 (8) ( 8 )   307-312 - 312   2007

人工骨で癌治療

日経産業新

2006.10

A novel hydroxyapatite fiber mesh as a carrier for recombinant human bone morphogenetic protein-2 enhances bone union in rat posterolateral fusion model

H Morisue, M Matsumoto, K Chiba, H Matsumoto, Y Toyama, M Aizawa, N Kanzawa, TJ Fujimi, H Uchida, Okada, I

SPINE   31 ( 11 )   1194 - 1200   2006.5

The effect of composition on PLGA/hydroxyapatite hybrid materials (III) -Biocompatibility of the hybrids in vitro

Miki Hayashi, Nami Sugiyama, Masahiro Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

Polymer Preprints, Japan   55 ( 2 )   5497 - 5498   2006

Fabrication and biocompatibility of poly(L-lactide)/hydroxyapatite composites (III) -Evaluation of biocompatibility for PLLA/HAp composites

Nami Sugiyama, Yoko Togashi, Masahiro Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

Polymer Preprints, Japan   55 ( 2 )   5495 - 5496   2006

Effect of hydrothermal treatment on poly(L-lactide)/hydroxyapatite hybridization

Takashi Iwasa, Nami Sugiyama, Masahiro Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

Polymer Preprints, Japan   55 ( 2 )   4914   2006

Investigation of composition effect on PLGA/hydroxyapatite hybrid materials (II) function of FL. -crystallinity and mechanical properties

Miki Hayashi, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa, Kohei Sanui

Polymer Preprints, Japan   55 ( 1 )   2035   2006

Development of Apatite Fiber Scaffolds Promoting Hard-Tissue Regeneration and Their Application to Biomedical Devices Reviewed

M. Aizawa, H. Uchida, I. Okada, T.J. Fujimi, N. Kanzawa, M. Matsumoto, H. Morisue, Y. Toyama

Archives of BioCeramic Research   6   9-12   2006

Apatite-Fiber Scaffolds provides Three-dimensional Culture Environment for Osteoblast-like cells. Reviewed

S. Izumi, M. Honda, N. Kanzawa, T.J. Fujimi, H. Uchida, T. Tsuchiya, H. Morisue, M. Matsumoto, M. Aizawa

Archives of BioCeramic Research   6   175-178   2006

Osteogenic differentiation in a three-dimensional apatite-fiber scaffold.

Honda M, Fujimi T.J, Kanzawa N, Izawa K, Tsuchiya T, Aizawa M

Arch. BioCeram. Res.   6   171 - 174   2006

Novel Properties of Apatite Fiber Produced by Controlling Orientation of Crystal Planes and Its Application to Tissue Engineering of Bone

AIZAWA Mamoru, MATSUMOTO Morio

Inorganic Materials   13 ( 324 )   345-352 - 352   2006

Syntheses of calcium-deficient apatite fibres by a homogeneous precipitation method and their characterizations

M Aizawa, H Ueno, K Itatani, Okada, I

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY   26 ( 4-5 )   501 - 507   2006

Syntheses of silicon-containing apatite fibres by a homogeneous precipitation method and their characterization

M Aizawa, N Patel, AE Porter, SM Best, W Bonfield

BIOCERAMICS 18, PTS 1 AND 2   309-311   1129 - 1132   2006

Effect of the concentrations of the starting solution on the syntheses and powder properties of hollow tricalcium-phosphate microspheres by ultrasonic spray-pyrolysis technique

T Ohno, M Aizawa

BIOCERAMICS 18, PTS 1 AND 2   309-311   235 - 238   2006

Adhesion, proliferation and morphology of osteoblasts cultured on apatite ceramics with preferred orientation to a-plane

A Miyazaki, M Aizawa

BIOCERAMICS 18, PTS 1 AND 2   309-311   109 - 112   2006

Development of Hydroxyapatite Fiber Scaffolds with Future Implication of Clinical Use

MATSUMOTO Morio, MORISUE Hikaru, AIZAWA Mamoru

Ceramics Japan   40 ( 10 )   865-868 - 868   2005.10

A peptide motif recognizing a polymer stereoregularity Reviewed

T Serizawa, T Sawada, H Matsuno, T Matsubara, T Sato

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   127 ( 40 )   13780 - 13781   2005.10

硬組織再生を促進するアパタイトファイバースキャフォルドの開発

相澤 守, 松本守雄

化学と工業   58 ( 9 )   1078-1081 - 1081   2005.9

Ultrastructural observation of single-crystal apatite fibres

M Aizawa, AE Porter, SM Best, W Bonfield

BIOMATERIALS   26 ( 17 )   3427 - 3433   2005.6

Ultrastructural observation of single-crystal apatite fibres

M Aizawa, AE Porter, SM Best, W Bonfield

BIOMATERIALS   26 ( 17 )   3427 - 3433   2005.6

MD simulation of crystal growth of NaCl from its supersaturated aqueous solution

Okada, I, Y Namiki, H Uchida, M Aizawa, K Itatani

JOURNAL OF MOLECULAR LIQUIDS   118 ( 1-3 )   131 - 139   2005.4

Characterization of porous beta-tricalcium phosphate films formed on alumina ceramics by spray-pyrolysis technique and their in vitro evaluations using osteoblasts

M Aizawa, K Itatani, Okada, I

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   113 ( 1315 )   245 - 251   2005.3

Fabrication and biocompatibility of poly(L-lactide)/hydroxyapatite composites (II) -In-vitro study for evaluating biocompatibility of PLLA/HAp composites

Yoko Togashi, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa, Kohei Sanui

Polymer Preprints, Japan   54 ( 2 )   4925 - 4926   2005

Investigation of composition effect on PLGA/hydroxyapatite hybrid materials

Miki Hayashi, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa, Kohei Sanui

Polymer Preprints, Japan   54 ( 2 )   4923 - 4924   2005

アパタイトファイバースキャフォルドのナノ構造と細胞分化

相澤 守, 神澤信行, 松本守雄

バイオマテリアル   23   336-342   2005

Three-dimensional cell culture of hepatocytes using apatite-fiber scaffold

A. Hiramoto, T. Matsuura, M. Aizawa

Archives of BioCeramics Research   5   238-241   2005

Synthesis of Calcium-phosphate Microsphere with well-controlled Particle Size by Ultrasonic Spray-pyrolysis Technique and Their Sinterability

M. Aizawa, A. Ono, T. Ohno, P-K. Choi

Phosphorus Res. Bull.   19   1-6   2005

Fabrication and Characterization of the Apatite-fiber Scaffolds with Enhanced Mechanical Property using Apatite Gels as a Sintering Agent

N. Igeta, T. Katakami, M. Aizawa

Phosphorus Res. Bull.,   19   42-47   2005

学会開催オーガナイザー(研究代表者);「第8回生体関連セラミックス討論会」

日本セラミックス協会生体関連材料部会で毎年開催している討論会, 第, 回生体関連セラミックス討論会, を明治大学にて, 日間開催, 口頭発表, 件および特別講演, 件。本プロジェクトの成果をその討論会において公表

2004.12

日経産業新聞 先端技術欄「生体修復に挑む 人工材料」に研究成果掲載

2004.11

日経産業新聞に研究成果掲載（すぐに固まる骨の補強材）

2004.10

日経産業新聞に研究成果掲載（立体形状の人工骨に）

2004.9

Development of porous ceramics with well-controlled porosities and pore sizes from apatite fibers and their evaluations

M Kawata, H Uchida, K Itatani, Okada, I, S Koda, M Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   15 ( 7 )   817 - 823   2004.7

“ティッシュエンジニアリングのための新しい三次元培養スキャフォルドの開発 －アパタイトファイバーによる骨化しやすいスポンジ状新材料－”

相澤 守, 松本守雄

遺伝子医学別冊 Bio Medical Quick Review Net   ( 4024 )   2004.5

“ティッシュエンジニアリングのためのアパタイトファイバーによる新規な三次元培養スキャフォルドの開発”

相澤 守, 篠田洋紀, 松本守雄

Phosphorus Letter   ( No. 51 )   3-12 - 12   2004

Fabrication of biodegradable polymer/hydroxyapatite hybrid materials

Y. Takeoka, R. Kunibu, M. Ishikawa, H. Yoshikawa, M. Aizawa, M. Rikukawa, K. Sanui

Transactions - 7th World Biomaterials Congress   991   2004

Development of porous tricalcium phosphate ceramics from calcium-phosphate fibers for a matrix of biodegradable ceramics/polymer hybrids

M. Aizawa, M. Ito, T. Miyashita, Y. Takeoka, M. Rikukawa, I. Okada

Transactions - 7th World Biomaterials Congress   982   2004

Microstructural changes of single-crystal apatite fibres during heat treatment

M Aizawa, AE Porter, SM Best, W Bonfield

BIOCERAMICS, VOL 16   254-2 ( 254-256 )   915 - 918   2004

“In Vitro Biological Evaluations of Three-Dimensional Scaffold Developed from Single-crystal Apatite Fibres for Tissue Engineering of Bone”,

M. Aizawa, H. Shinoda, H. Uchida, I. Okada, T. J. Fujimi, N. Kanzawa, H. Morisue, M. Matsumoto, Y. Toyama

Phosphorus Res. Bull.   17 ( 17 )   268-273 - 273   2004

“Fabrication of Porous Tricalcium Phosphate Ceramics from Calcium-phosphate Fibers for a Matrix of Biodegradable Ceramics/polymer Hybrids”

M. Aizawa, M. Ito, Y. Takeoka, M. Rikukawa, I. Okada

Phosphorus Res. Bull.   ( 17 )   213-214   2004

“Biocompatibility of Hydroxyapatite Films Formed on Various Metals by a Surface Treatment Using an Enzyme Reaction”

J. Nozaki, H. Uchida, K. Itatani, I. Okada, S. Koda, M. Aizawa, M. Matsumoto, H. Matsumoto, Y. Toyama

Trans. Mater. Res. Soc. Jpn.   ( 29 )   2663-2666   2004

日刊工業新聞に研究成果掲載（少しの苦痛で骨修復）

2003.10

日経産業新聞に研究成果掲載（骨化しやすい材料開発）

2003.10

Fabrication and electrical properties of proton conducting polymer hybridized with apatite compounds

K Kaneko, Y Takeoka, M Aizawa, M Rikukawa

SYNTHETIC METALS   135 ( 1-3 )   73 - 74   2003.4

MD simulation of crystal growth from CaCl2 melt Reviewed

Okada, I, Y Abe, K Nakata, S Baluja, M Aizawa, H Uchida, K Itatani

JOURNAL OF MOLECULAR LIQUIDS   103   371 - 385   2003.3

High resolution transmission electron microscopy investigation of single crystal apatite fibres synthesized by a homogeneous precipitation method

M Aizawa, AE Porter, SM Best, W Bonfield

BIOCERAMICS 15   240-2 ( 240-242 )   509 - 512   2003

“Development of Scaffolds for Tissue Engineering Using Single-crystal Apatite Fibres and Their Biological Evaluation by Osteoblastic Cell”

M. Aizawa, H. Ueno, I. Okada

Trans. Mater. Res. Soc. Jpn.   ( 28 )   849-852   2003

“Development of novel cement processing using hydroxyapatite particles modified with inositol phosphate”

M. Aizawa, Y. Haruta, I. Okada

Archives of BioCeramics Research   ( 3 )   134-138   2003

Development and biological evaluation of apatite fibre scaffolds with large pore size and high porosity for bone regeneration

M Aizawa, H Shinoda, H Uchida, K Itatani, Okada, I, M Matsumoto, Y Toyama

BIOCERAMICS 15   240-2 ( 240-242 )   647 - 650   2003

Densification and mechanical properties of 4AlN-SiC ceramics - Utilization of nanocomposite powders prepared by the nitridation of aluminum silicon carbide

K Itatani, R Tsukamoto, H Uchida, M Aizawa, ACA Delsing, HT Hintzen, Okada, I

ADVANCED CERAMICS AND COMPOSITES   247 ( 247 )   91 - 94   2003

Biocompatibility of hydroxyapatite films formed on Ti metal by a simple urea and urease treatment

J Nozaki, M Aizawa, H Uchida, K Itatani, H Suemasu, A Nozue, Okada, I, M Matsumoto, H Matsumoto, Y Toyama

BIOCERAMICS 15   240-2 ( 240-242 )   603 - 606   2003

Fabrication of Multi-Functional Ceramics by the Utilization of Spray-Pyrolysis Technique

ITATANI Kiyoshi, AIZAWA Mamoru

Inorganic Materials   10 ( 10 )   285-292 - 292   2003

“Acoustic Emission From Micro-fracture Processes of Bio-ceramics in Simulated Body Environment”

S. Wakayama, T. Kawakami, S. Kobayashi, M. Aizawa, A. Nozue

J. Acoustic Emission   ( 21 )   149-156   2003

“脊椎固定術における生体材料 －最近の試みと今後の展望”, 骨・関節・靭帯

松本守雄, 千葉一裕, 戸山芳昭, 相澤守

[解説]   ( 16 )   239-245   2003

“無機/有機ハイブリッドによる生体活性テーラードマテリアルの創製”

相澤守, 伊藤まどか, 板谷清司, 岡田勲, 松本守雄

Phosphorus Letter[解説]   ( 46 )   7-14   2003

Effect of metal-oxide addition on the sintering of beta-calcium orthophosphate

K Itatani, M Takahashi, FS Howell, M Aizawa

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE   13 ( 7 )   707 - 713   2002.7

The effect of rare-earth oxide addition on the hot-pressing of magnesium silicon nitride

S Tanaka, K Itatani, H Uchida, M Aizawa, IJ Davies, H Suemasu, A Nozue, Okada, I

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY   22 ( 5 )   777 - 783   2002.5

MD simulation of crystal growth from MgO melt

Okada, I, Y Utsunomiya, H Uchida, M Aizawa

JOURNAL OF MOLECULAR LIQUIDS   98-9 ( 98-99 )   191 - 200   2002.5

Sinterability of magnesium silicon nitride powder with yttrium oxide addition coated using the homogeneous precipitation method

K Itatani, IJ Davies, H Kuwano, M Aizawa

JOURNAL OF MATERIALS SCIENCE   37 ( 4 )   737 - 744   2002.2

Densification and microstructural developments during the sintering of aluminium silicon carbide

K Itatani, F Takahashi, M Aizawa, Okada, I, IJ Davies, H Suemasu, A Nozue

JOURNAL OF MATERIALS SCIENCE   37 ( 2 )   335 - 342   2002.1

Coating of hydroxyapatite films on ceria-stabilized tetragonal zirconia by a spray-pyrolysis technique and its evaluation of biocompatibility by osteoblastic cells

W Nishine, M Aizawa, M Nawa, K Itatani, H Suemasu, A Nozue, Okada, I

BIOCERAMICS 14   218-2 ( 218-220 )   213 - 216   2002

Coating of hydroxyapatite films on ceria-stabilized tetragonal zirconia by a spray-pyrolysis technique and its evaluation of biocompatibility by osteoblastic cells

W Nishine, M Aizawa, M Nawa, K Itatani, H Suemasu, A Nozue, Okada, I

BIOCERAMICS 14   218-2   213 - 216   2002

In vivo and in vitro evaluation of the biocompatibility of the hydroxyapatite-PMMA hybrid materials having mechanical property similar to that of cortical bone

M Aizawa, M Ito, K Itatani, H Suemasu, A Nozue, Okada, I, M Matsumoto, M Ishikawa, H Matsumoto, Y Toyama

BIOCERAMICS 14   218-2 ( 218-220 )   465 - 468   2002

"In vivo and In vitro Evaluation of the Biocompatibility of the Hydroxyapatite-PMMA Hybrid Materials Having Mechanical Property Similar to That of Cortical Bone"

M. Aizawa, M. Ito, K. Itatani, H. Suemasu, A. Nozue, I. Okada, M. Matsumoto, M. Ishikawa, H. Matsumoto, Y. Toyama

14th International Symposium on Cearamics in Medicine, Parm Spring, US   14-17 November   2001.10

Sinterability of β-SiAlON powder prepared by carbothermal reduction and simultaneous nitridation of ultrafine powder in the Al2O3-SiO2 system

I. J. Davies, T. Minemura, N. Mizutani, M. Aizawa, K. Itatani

Journal of Materials Science   36 ( 1 )   165 - 172   2001.1

Some properties of silicon carbide composites fabricated with chopped Si-Al-C fibers

K Itatani, T Tanaka, IJ Davies, M Aizawa, Okada, I, H Suemasu, A Nozue

INTERNATIONAL JOURNAL OF MATERIALS & PRODUCT TECHNOLOGY   16 ( 1-3 )   239 - 247   2001

Mechanical and thermal properties of silicon-carbide composites fabricated with short Tyranno (R) Si-Zr-C-O fibre

K Itatani, K Hattori, D Harima, M Aizawa, Okada, I, IJ Davies, H Suemasu, A Nozue

JOURNAL OF MATERIALS SCIENCE   36 ( 15 )   3679 - 3686   2001

Fabrication of porous ceramics with well-controlled open pores by sintering of fibrous hydroxyapatite particles

M Aizawa, FS Howell, K Itatani, Y Yokogawa, K Nishizawa, M Toriyama, T Kameyama

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   108 ( 3 )   249 - 253   2000.3

Preparation of various calcium-phosphate powders by ultrasonic spray freeze-drying technique

K Itatani, K Iwafune, FS Howell, M Aizawa

MATERIALS RESEARCH BULLETIN   35 ( 4 )   575 - 585   2000.3

Formation of calcium-phosphate films with gradient composition on alumina ceramics by spray-pyrolysis technique and their biocompatibilities by cell-culture tests

M Aizawa, T Yamamoto, K Itatani, H Suemasu, A Nozue, Okada, I

BIOCERAMICS   192-1 ( 192-195 )   103 - 106   2000

"Sinterability of Apatite-Zirconia Composite Powder Prepared by Ultrasonic Spary Freeze-Drying Technique".

K. Itatani, K. Akiyama, M. Aizawa, F. S. Howell, I. Okada

J. Soc. Inorg. Mater. Jpn.   ( 7 )   194-202   2000

"Formation of Carbonate-containing Hydroxyapatite Film on Ti substrate by a Simple Surface Treatment Utilizing an Enzyme Reaction"

M. Aizawa, M. Yoshihama, I. Okada

International Symposium on Soft Solution Processing (SSP-2000), Dec. 11-13, Tokyo   2000

Formation of calcium-phosphate films with gradient composition on alumina ceramics by spray-pyrolysis technique and their biocompatibilities by cell-culture tests

M Aizawa, T Yamamoto, K Itatani, H Suemasu, A Nozue, Okada, I

BIOCERAMICS   192-1   103 - 106   2000

"Fabrication of Porous Spinel (MgAl_2_O_4_)-Zriconia Ceramics from the Powder Prepared by Ultrasonic Spray Pyrolysis".

K. Itatani, N. Morita, S. Ohkubo, T. Suzuki, F. S. Howell, M. Aizawa

J. Soc. Inorg. Mater. Jpn.   ( 7 )   33-39   2000

"Biocompatibility of Porous β-Tricacium Phosphate Films on the Zirconia Ceramics Formed by Spray-pyrolysis Technique"

M. Aizawa

Phosphorus Res. Bull.   ( 11 )   19-24   2000

"レーザーアブレーション法による水酸アパタイト膜の作製"

板谷清司, 相澤守

Phosphorus Letter[トッピクス]   ( 37 )   28-32 - 32   2000

Characterization of strontiumapatite powders prepared by ultrasonic spray-pyrolysis technique

M Aizawa, FS Howell, K Itatani

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   107 ( 11 )   1007 - 1011   1999.11

Preparation of spherical apatite particles by the homogeneous precipitation method in the presence of magnesium ions and their ion-exchange properties

M Aizawa, T Terado, FS Howell, K Itatani

MATERIALS RESEARCH BULLETIN   34 ( 8 )   1215 - 1225   1999.6

Characterization of hydroxyapatite powders prepared by ultrasonic spray-pyrolysis technique

M Aizawa, T Hanazawa, K Itatani, FS Howell, A Kishioka

JOURNAL OF MATERIALS SCIENCE   34 ( 12 )   2865 - 2873   1999.6

"繊維状アパタイトによる細胞培養用多孔質シートの作製"

相澤守, 上野宏子, 板谷清司

マテリアルインテグレーション[研究速報]   12 ( 12 )   75-77 - 77   1999

Preparation of magnesium silicon nitride powder by the carbothermal reduction technique

H Uchida, K Itatani, M Aizawa, FS Howell, A Kishioka

ADVANCED POWDER TECHNOLOGY   10 ( 2 )   133 - 143   1999

"Physical Properties of Hot-pressed Magnesium Silicon Nitride Compacts with Yttrium Oxide Addition"

I. J. Davies, T. Shimazaki, M. Aizawa, H. Suemasu, A. Nozue, K. Itatani

Inorg. Mater.   6 ( 6 )   276-284 - 284   1999

"Physical and Mechanical Properties of Sintered Magnesium Silicon Nitride Compacts with Yttrium Oxide Addition"

I. J. Davies, H. Uchida, M. Aizawa, K. Itatani

Inorg. Mater.   6 ( 6 )   40-47 - 47   1999

"Fabrication of Hybrid Materials by the Introducton of Poly(methylmethacrylate) into the Porous Hydroxyapatite Ceramics"

M. Aizawa, Y. Tsuchiya, K. Itatani, H. Suemasu, A. Nozue, I. Okada

Bioceramics   ( 12 )   453-456   1999

"Coating of porous hydroxyapatite films on the alumina ceramics by spray-pyrolysis technique and their biocompatibility"

M. Aizawa, T. Yamamoto, K. Itatani, H. Suemasu, A. Nozue, I. Okada

Phosphorus Res. Bull.   ( 10 )   283-288   1999

"Characterization of the magnesium-substituted hydroxyapatite prepared by ultrasonic spray-pyrolysis technique"

T. Hanazawa, M. Aizawa, F. S. Howel, K. Itatani

Phosphorus Res. Bull.   ( 9 )   5-10   1999

Sintering of mullite-zirconia composite powder prepared by ultrasonic spray pyrolysis technique

K Itatani, T Abiko, M Aizawa, FS Howell, A Kishioka

JOURNAL OF MATERIALS SYNTHESIS AND PROCESSING   6 ( 3 )   221 - 225   1998.5

Effects of Additives on Synthesis and Morphology of Carbonate-Containing Hydroxyapatite Prepared by Homogeneous Precipitation Method

AIZAWA Mamoru, KINOSHITA Makio, YAMADA Kohji, ITATANI Kiyoshi, KISHIOKA Akira

Journal of the Society of Inorganic Materials, Japan   5 ( 5 )   387-397 - 397   1998

"Preparation and Properties of Glasses Containing Large Amounts of Titanium (IV) in Na_2_O-TiO_2_-P_2_O_5_ System"

A. Kishioka, Y. Nishi, M. Aizawa, K. Itatani, F. S. Howell

Inorganic Materials   5 ( 5 )   220-224 - 224   1998

"噴霧熱分解法による生体適合成膜の形成"

相澤守, 板谷清司

表面[解説]   ( 36 )   676-686   1998

, "Properties of the composite fabricated by the introduction of silicone into the porous hydroxyapatite ceramics"

M. Aizawa, T. Shimizu, K. Itatani, F. S. Howell, A. Kishioka

Phosphorus Res. Bull.   ( 8 )   43-48   1998

"バイオミメティックプロセスによる無機薄膜の形成"

相澤守

化学と工業[トピックス]   ( 51 )   617   1998

Synthesis of magnesium silicon nitride by the nitridation of powders in the magnesium-silicon system

H Uchida, K Itatani, M Aizawa, FS Howell, A Kishioka

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   105 ( 11 )   934 - 939   1997.11

Synthesis of Magnesium Silicon Nitride by the Nitridation of Powders in the Magnesium-Silicon System Reviewed

Hiroshi UCHIDA, Kiyoshi ITATANI, Mamoru AIZAWA, Frank Scott HOWELL, Akira KISHIOKA

Journal of the Ceramic Society of Japan   105 ( 1227 )   934 - 939   1997.11

"水熱処理によるCaO-P_2_O_5_-SiO_2_系セラミックスへの水酸アパタイトコーティング"

相澤守, 板谷清司, 岸岡昭

Phosphorus Letter[解説]   ( 28 )   3-8 - 8   1997

Effects of starting materials on properties of hydroxyapatite powders prepared by spray-pyrolysis technique

M Aizawa, K Itatani, FS Howell, A Kishioka

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   104 ( 2 )   126 - 132   1996.2

Effects of starting materials on properties of hydroxyapatite powders prepared by spray-pyrolysis technique Reviewed

M Aizawa, K Itatani, FS Howell, A Kishioka

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   104 ( 2 )   126 - 132   1996.2

Low-temperature synthesis of aluminum silicon carbide using ultrafine aluminum carbide and silicon carbide powders Reviewed

M Hasegawa, K Itatani, M Aizawa, FS Howell, A Kishioka

JOURNAL OF THE AMERICAN CERAMIC SOCIETY   79 ( 1 )   275 - 278   1996.1

Low-temperature synthesis of aluminum silicon carbide using ultrafine aluminum carbide and silicon carbide powders

M Hasegawa, K Itatani, M Aizawa, FS Howell, A Kishioka

JOURNAL OF THE AMERICAN CERAMIC SOCIETY   79 ( 1 )   275 - 278   1996.1

"Characterization of various apatites powders prepared by ultrasonic spray-pyrolysis technique"

M. Aizawa, T. Hanazawa, K. Itatani, F. S. Howell, A. Kishioka

Phosphorus Res. Bull.   ( 6 )   217-220   1996

Sinterability of spinel (MgAl2O4)-zirconia composite powder prepared by double nozzle ultrasonic spray pyrolysis

T Suzuki, K Itatani, M Aizawa, FS Howell, A Kishioka

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY   16 ( 11 )   1171 - 1178   1996

Sinterability of spinel (MgAl2O4)-zirconia composite powder prepared by double nozzle ultrasonic spray pyrolysis

T Suzuki, K Itatani, M Aizawa, FS Howell, A Kishioka

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY   16 ( 11 )   1171 - 1178   1996

Effects of various metal-oxide additions on sintering of β-calcium orthophosphate prepared by spray-pyrolysis Reviewed

K. Itatani, M. Takahashi, M. Aizawa, F. S. Howell, A. Kishioka

Phosphorus Res. Bull.   ( 6 )   171 - 174   1996

Characterization of various apatites powders prepared by ultrasonic spray-pyrolysis technique Reviewed

M. Aizawa, T. Hanazawa, K. Itatani, F. S. Howell, A. Kishioka

Phosphorus Res. Bull., 6, 217-220 (1996)   ( 6 )   217 - 220   1996

"Sinterability of Hydroxyapatite-Zirconia Composite Powder Prepared by Double Nozzle Spray Pyrolysis"

K. Itatani, M. Aizawa, H. Kano, F. S. Howell, A. Kishioka

Inorganic Materials   ( 3 )   102-110   1996

"Effects of various metal-oxide additions on sintering of β-calcium orthophosphate prepared by spray-pyrolysis"

K. Itatani, M. Takahashi, M. Aizawa, F. S. Howell, A. Kishioka

Phosphorus Res. Bull.   ( 6 )   171-174   1996

Some properties of carbonate-containing hydroxyapatite powder prepared by spray-pyrolysis technique using urea as a foaming agent

M Aizawa, K Itatani, FS Howell, A Kishioka

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 12 )   1214 - 1219   1995.12

Some properties of carbonate-containing hydroxyapatite powder prepared by spray-pyrolysis technique using urea as a foaming agent Reviewed

M Aizawa, K Itatani, FS Howell, A Kishioka

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 12 )   1214 - 1219   1995.12

Formation of Hydroxyapatite on Composites in CaO-P_2O_5-SiO_2-Al_2O_3 System by Hydrothermal Treatment

AIZAWA Mamoru, ISHIKAWA Taro, ITATANI Kiyoshi, HOWELL F.S., KINOSHITA Makio, KISHIOKA Akira

Journal of the Ceramic Society of Japan   103 ( 1202 )   992 - 995   1995.10

FORMATION OF POROUS CALCIUM-PHOSPHATE FILMS ON PARTIALLY-STABILIZED ZIRCONIA SUBSTRATES BY THE SPRAY-PYROLYSIS TECHNIQUE

M AIZAWA, K ITATANI, FS HOWELL, A KISHIOKA, M KINOSHITA

JOURNAL OF MATERIALS SCIENCE   30 ( 19 )   4936 - 4945   1995.10

FORMATION OF HYDROXYAPATITE ON COMPOSITES IN CAO-P2O5-SIO2-AL2O3 SYSTEM BY HYDROTHERMAL TREATMENT Reviewed

M AIZAWA, T ISHIKAWA, K ITATANI, FS HOWELL, M KINOSHITA, A KISHIOKA

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 10 )   992 - 995   1995.10

FORMATION OF HYDROXYAPATITE ON COMPOSITES IN CAO-P2O5-SIO2-AL2O3 SYSTEM BY HYDROTHERMAL TREATMENT

M AIZAWA, T ISHIKAWA, K ITATANI, FS HOWELL, M KINOSHITA, A KISHIOKA

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 10 )   992 - 995   1995.10

FORMATION OF POROUS CALCIUM-PHOSPHATE FILMS ON PARTIALLY-STABILIZED ZIRCONIA SUBSTRATES BY THE SPRAY-PYROLYSIS TECHNIQUE Reviewed

M AIZAWA, K ITATANI, FS HOWELL, A KISHIOKA, M KINOSHITA

JOURNAL OF MATERIALS SCIENCE   30 ( 19 )   4936 - 4945   1995.10

PRECIPITATION OF HYDROXYAPATITE THROUGH HYDROTHERMAL TREATMENT OF THE COMPOSITES IN THE CAO-P2O5-SIO2-B2O3 SYSTEM PREPARED BY SOL-GEL PROCESS

M AIZAWA, K ITATANI, FS HOWELL, M KINOSHITA, A KISHIOKA

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 8 )   777 - 781   1995.8

PRECIPITATION OF HYDROXYAPATITE THROUGH HYDROTHERMAL TREATMENT OF THE COMPOSITES IN THE CAO-P2O5-SIO2-B2O3 SYSTEM PREPARED BY SOL-GEL PROCESS Reviewed

M AIZAWA, K ITATANI, FS HOWELL, M KINOSHITA, A KISHIOKA

JOURNAL OF THE CERAMIC SOCIETY OF JAPAN   103 ( 8 )   777 - 781   1995.8